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Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
Renga B, Bucci M, Cipriani S, Carino A, Monti MC, Zampella A, Gargiulo A, d'Emmanuele di Villa Bianca R, Distrutti E, Fiorucci S. Renga B, et al. Among authors: bucci m. Am J Physiol Heart Circ Physiol. 2015 Jul 1;309(1):H114-26. doi: 10.1152/ajpheart.00087.2015. Epub 2015 May 1. Am J Physiol Heart Circ Physiol. 2015. PMID: 25934094 Free article.
Proteinase-activated receptor-2 mediates arterial vasodilation in diabetes.
Roviezzo F, Bucci M, Brancaleone V, Di Lorenzo A, Geppetti P, Farneti S, Parente L, Lungarella G, Fiorucci S, Cirino G. Roviezzo F, et al. Among authors: bucci m. Arterioscler Thromb Vasc Biol. 2005 Nov;25(11):2349-54. doi: 10.1161/01.ATV.0000184770.01494.2e. Epub 2005 Sep 1. Arterioscler Thromb Vasc Biol. 2005. PMID: 16141401
Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity.
Bucci M, Papapetropoulos A, Vellecco V, Zhou Z, Pyriochou A, Roussos C, Roviezzo F, Brancaleone V, Cirino G. Bucci M, et al. Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):1998-2004. doi: 10.1161/ATVBAHA.110.209783. Epub 2010 Jul 15. Arterioscler Thromb Vasc Biol. 2010. PMID: 20634473
741 results