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SAR refinement of antileishmanial N(2),N(4)-disubstituted quinazoline-2,4-diamines.
Bioorg Med Chem. 2015 Aug 15;23(16):5182-9. doi: 10.1016/j.bmc.2015.02.020. Epub 2015 Feb 18.
Bioorg Med Chem. 2015.
PMID: 25749014
Free PMC article.
Antibacterial activity of a series of N2,N4-disubstituted quinazoline-2,4-diamines.
Van Horn KS, Burda WN, Fleeman R, Shaw LN, Manetsch R.
Van Horn KS, et al.
J Med Chem. 2014 Apr 10;57(7):3075-93. doi: 10.1021/jm500039e. Epub 2014 Mar 31.
J Med Chem. 2014.
PMID: 24625106
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Antileishmanial activity of a series of N²,N⁴-disubstituted quinazoline-2,4-diamines.
Van Horn KS, Zhu X, Pandharkar T, Yang S, Vesely B, Vanaerschot M, Dujardin JC, Rijal S, Kyle DE, Wang MZ, Werbovetz KA, Manetsch R.
Van Horn KS, et al.
J Med Chem. 2014 Jun 26;57(12):5141-56. doi: 10.1021/jm5000408. Epub 2014 Jun 17.
J Med Chem. 2014.
PMID: 24874647
Free PMC article.
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Characterizing the Antimicrobial Activity of N2,N4-Disubstituted Quinazoline-2,4-Diamines toward Multidrug-Resistant Acinetobacter baumannii.
Fleeman R, Van Horn KS, Barber MM, Burda WN, Flanigan DL, Manetsch R, Shaw LN.
Fleeman R, et al. Among authors: van horn ks.
Antimicrob Agents Chemother. 2017 May 24;61(6):e00059-17. doi: 10.1128/AAC.00059-17. Print 2017 Jun.
Antimicrob Agents Chemother. 2017.
PMID: 28289036
Free PMC article.
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Correction to Antileishmanial Activity of a Series of N(2),N(4)-Disubstituted Quinazoline-2,4-diamines.
Van Horn KS, Zhu X, Pandharkar T, Yang S, Vesely B, Vanaerschot M, Dujardin JC, Rijal S, Kyle DE, Wang MZ, Werbovetz KA, Manetsch R.
Van Horn KS, et al.
J Med Chem. 2016 Jan 28;59(2):775. doi: 10.1021/acs.jmedchem.5b00981. Epub 2016 Jan 12.
J Med Chem. 2016.
PMID: 26754204
No abstract available.
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Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6.
Van Horn KS, Wang D, Medina-Cleghorn D, Lee PS, Bryant C, Altobelli C, Jaishankar P, Leung KK, Ng RA, Ambrose AJ, Tang Y, Arkin MR, Renslo AR.
Van Horn KS, et al.
J Am Chem Soc. 2023 May 10;145(18):10015-10021. doi: 10.1021/jacs.2c12240. Epub 2023 Apr 27.
J Am Chem Soc. 2023.
PMID: 37104712
Free PMC article.
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