Newman J - Search Results

1

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

Dennis ML, Chhabra S, Wang ZC, Debono A, Dolezal O, Newman J, Pitcher NP, Rahmani R, Cleary B, Barlow N, Hattarki M, Graham B, Peat TS, Baell JB, Swarbrick JD. Dennis ML, et al. Among authors: newman j. J Med Chem. 2014 Nov 26;57(22):9612-26. doi: 10.1021/jm501417f. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25357262

2

Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 A resolution.

Peat TS, Newman J, Waldo GS, Berendzen J, Terwilliger TC. Peat TS, et al. Among authors: newman j. Structure. 1998 Sep 15;6(9):1207-14. doi: 10.1016/s0969-2126(98)00120-8. Structure. 1998. PMID: 9753699 Free article.

3

A nondenaturing purification scheme for the DNA-binding domain of poly(ADP-ribose) polymerase, a structure-specific DNA-binding protein.

Ruscetti T, Newman J, Peat TS, Francis J, Nolan R, Terwilliger TC, Peterson SR, Lehnert BE. Ruscetti T, et al. Among authors: newman j. Protein Expr Purif. 1998 Oct;14(1):79-86. doi: 10.1006/prep.1998.0919. Protein Expr Purif. 1998. PMID: 9758754

4

Haloalkane dehalogenases: structure of a Rhodococcus enzyme.

Newman J, Peat TS, Richard R, Kan L, Swanson PE, Affholter JA, Holmes IH, Schindler JF, Unkefer CJ, Terwilliger TC. Newman J, et al. Biochemistry. 1999 Dec 7;38(49):16105-14. doi: 10.1021/bi9913855. Biochemistry. 1999. PMID: 10587433

5

Tapping the Protein Data Bank for crystallization information.

Peat TS, Christopher JA, Newman J. Peat TS, et al. Among authors: newman j. Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1662-9. doi: 10.1107/S0907444905033202. Epub 2005 Nov 19. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 16301801

6

Phoenito experiments: combining the strengths of commercial crystallization automation.

Newman J, Pham TM, Peat TS. Newman J, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Nov 1;64(Pt 11):991-6. doi: 10.1107/S1744309108029667. Epub 2008 Oct 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18997323 Free PMC article.

7

Structural genomics in the post-genomics era - the shapes of things to come.

Peat TS, Newman JM, Bussiere DE. Peat TS, et al. Among authors: newman jm. Curr Opin Drug Discov Devel. 2000 Jul;3(4):399-407. Curr Opin Drug Discov Devel. 2000. PMID: 19649871

8

Crystallization and preliminary X-ray analysis of the complexes between a Fab and two forms of human insulin-like growth factor II.

Newman J, Cohen EH, Cosgrove L, Kopacz K, Dransfield DT, Adams TE, Peat TS. Newman J, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt 9):945-8. doi: 10.1107/S1744309109024932. Epub 2009 Aug 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19724140 Free PMC article.

9

Practical aspects of the SAMPL challenge: providing an extensive experimental data set for the modeling community.

Newman J, Fazio VJ, Caradoc-Davies TT, Branson K, Peat TS. Newman J, et al. J Biomol Screen. 2009 Dec;14(10):1245-50. doi: 10.1177/1087057109348220. J Biomol Screen. 2009. PMID: 19822883

10

Germline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment.

Robert R, Streltsov VA, Newman J, Pearce LA, Wark KL, Dolezal O. Robert R, et al. Among authors: newman j. Protein Sci. 2010 Feb;19(2):299-308. doi: 10.1002/pro.312. Protein Sci. 2010. PMID: 20014445 Free PMC article.

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