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Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI. Madiraju AK, et al. Among authors: wood jl. Nature. 2014 Jun 26;510(7506):542-6. doi: 10.1038/nature13270. Epub 2014 May 21. Nature. 2014. PMID: 24847880 Free PMC article.
A chemical switch for inhibitor-sensitive alleles of any protein kinase.
Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM. Bishop AC, et al. Among authors: wood jl. Nature. 2000 Sep 21;407(6802):395-401. doi: 10.1038/35030148. Nature. 2000. PMID: 11014197
The first synthesis of an epidiselenodiketopiperazine.
McMahon TC, Stanley S, Kazyanskaya E, Hung D, Wood JL. McMahon TC, et al. Among authors: wood jl. Org Lett. 2012 Sep 7;14(17):4534-6. doi: 10.1021/ol3020094. Epub 2012 Aug 22. Org Lett. 2012. PMID: 22913407
Toward the synthesis of phomoidride D.
Murphy GK, Shirahata T, Hama N, Bedermann A, Dong P, McMahon TC, Twenter BM, Spiegel DA, McDonald IM, Taniguchi N, Inoue M, Wood JL. Murphy GK, et al. Among authors: wood jl. J Org Chem. 2013 Jan 18;78(2):477-89. doi: 10.1021/jo302353g. Epub 2013 Jan 10. J Org Chem. 2013. PMID: 23245580
Total syntheses of (±)-securinine and (±)- allosecurinine.
Chen JH, Levine SR, Buergler JF, McMahon TC, Medeiros MR, Wood JL. Chen JH, et al. Among authors: wood jl. Org Lett. 2012 Sep 7;14(17):4531-3. doi: 10.1021/ol3020072. Epub 2012 Aug 22. Org Lett. 2012. PMID: 22913575
570 results