Synthetic studies toward the citrinadins: enantioselective preparation of an advanced spirooxindole intermediate

Tetrahedron. 2014 Jul 8;70(27-28):4089-4093. doi: 10.1016/j.tet.2014.02.046. Epub 2014 Feb 25.

Authors

Takanori Matsumaru¹, Monica E McCallum¹, John A Enquist Jr¹, Genessa M Smith¹, Ke Kong¹, John L Wood¹

Affiliation

¹ Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76798.

Abstract

This manuscript describes the enantioselective preparation of a spirooxindole that is suited for advancedment to either Citrinadin A or B.

Keywords: Citrinadin; Heck reaction; natural product; spirooxindole; synthesis.

Grants and funding

F32 GM095076/GM/NIGMS NIH HHS/United States