Worthington RJ - Search Results

1

Nanoscale structure-activity relationships, mode of action, and biocompatibility of gold nanoparticle antibiotics.

Bresee J, Bond CM, Worthington RJ, Smith CA, Gifford JC, Simpson CA, Carter CJ, Wang G, Hartman J, Osbaugh NA, Shoemaker RK, Melander C, Feldheim DL. Bresee J, et al. Among authors: worthington rj. J Am Chem Soc. 2014 Apr 9;136(14):5295-300. doi: 10.1021/ja408505n. Epub 2014 Mar 27. J Am Chem Soc. 2014. PMID: 24624950

2

Overcoming resistance to β-lactam antibiotics.

Worthington RJ, Melander C. Worthington RJ, et al. J Org Chem. 2013 May 3;78(9):4207-13. doi: 10.1021/jo400236f. Epub 2013 Mar 28. J Org Chem. 2013. PMID: 23530949 Free PMC article. Review.

3

A facile synthesis of 1,5-disubstituted-2-aminoimidazoles: antibiotic activity of a first generation library.

Harris TL, Worthington RJ, Melander C. Harris TL, et al. Among authors: worthington rj. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4516-9. doi: 10.1016/j.bmcl.2011.05.123. Epub 2011 Jun 15. Bioorg Med Chem Lett. 2011. PMID: 21737267

4

Intercepting bacterial indole signaling with flustramine derivatives.

Bunders CA, Minvielle MJ, Worthington RJ, Ortiz M, Cavanagh J, Melander C. Bunders CA, et al. Among authors: worthington rj. J Am Chem Soc. 2011 Dec 21;133(50):20160-3. doi: 10.1021/ja209836z. Epub 2011 Nov 22. J Am Chem Soc. 2011. PMID: 22091927 Free PMC article.

5

Potent small-molecule suppression of oxacillin resistance in methicillin-resistant Staphylococcus aureus.

Harris TL, Worthington RJ, Melander C. Harris TL, et al. Among authors: worthington rj. Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11254-7. doi: 10.1002/anie.201206911. Epub 2012 Oct 9. Angew Chem Int Ed Engl. 2012. PMID: 23047322 Free PMC article.

6

Combination approaches to combat multidrug-resistant bacteria.

Worthington RJ, Melander C. Worthington RJ, et al. Trends Biotechnol. 2013 Mar;31(3):177-84. doi: 10.1016/j.tibtech.2012.12.006. Epub 2013 Jan 18. Trends Biotechnol. 2013. PMID: 23333434 Free PMC article. Review.

7

Small molecule downregulation of PmrAB reverses lipid A modification and breaks colistin resistance.

Harris TL, Worthington RJ, Hittle LE, Zurawski DV, Ernst RK, Melander C. Harris TL, et al. Among authors: worthington rj. ACS Chem Biol. 2014 Jan 17;9(1):122-7. doi: 10.1021/cb400490k. Epub 2013 Oct 28. ACS Chem Biol. 2014. PMID: 24131198

8

Evaluation of 4,5-disubstituted-2-aminoimidazole-triazole conjugates for antibiofilm/antibiotic resensitization activity against MRSA and Acinetobacter baumannii.

Su Z, Peng L, Worthington RJ, Melander C. Su Z, et al. Among authors: worthington rj. ChemMedChem. 2011 Dec 9;6(12):2243-51. doi: 10.1002/cmdc.201100316. Epub 2011 Sep 16. ChemMedChem. 2011. PMID: 21928438

9

Biologically inspired strategies for combating bacterial biofilms.

Blackledge MS, Worthington RJ, Melander C. Blackledge MS, et al. Among authors: worthington rj. Curr Opin Pharmacol. 2013 Oct;13(5):699-706. doi: 10.1016/j.coph.2013.07.004. Epub 2013 Jul 18. Curr Opin Pharmacol. 2013. PMID: 23871261 Free PMC article. Review.

10

Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence.

Worthington RJ, Blackledge MS, Melander C. Worthington RJ, et al. Future Med Chem. 2013 Jul;5(11):1265-84. doi: 10.4155/fmc.13.58. Future Med Chem. 2013. PMID: 23859207 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

23 results

Search Page