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NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, Ting JP. Zhang L, et al. Among authors: fitzgerald ka. Immunity. 2014 Mar 20;40(3):329-41. doi: 10.1016/j.immuni.2014.01.010. Epub 2014 Feb 20. Immunity. 2014. PMID: 24560620 Free PMC article.
IFI16 is an innate immune sensor for intracellular DNA.
Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, Sirois CM, Jin T, Latz E, Xiao TS, Fitzgerald KA, Paludan SR, Bowie AG. Unterholzner L, et al. Among authors: fitzgerald ka. Nat Immunol. 2010 Nov;11(11):997-1004. doi: 10.1038/ni.1932. Epub 2010 Oct 3. Nat Immunol. 2010. PMID: 20890285 Free PMC article.
Innate immune sensing of DNA viruses.
Rathinam VA, Fitzgerald KA. Rathinam VA, et al. Among authors: fitzgerald ka. Virology. 2011 Mar 15;411(2):153-62. doi: 10.1016/j.virol.2011.02.003. Epub 2011 Feb 18. Virology. 2011. PMID: 21334037 Free PMC article. Review.
Innate immune sensing of DNA.
Sharma S, Fitzgerald KA. Sharma S, et al. Among authors: fitzgerald ka. PLoS Pathog. 2011 Apr;7(4):e1001310. doi: 10.1371/journal.ppat.1001310. Epub 2011 Apr 21. PLoS Pathog. 2011. PMID: 21533068 Free PMC article. Review. No abstract available.
Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Sharma S, DeOliveira RB, Kalantari P, Parroche P, Goutagny N, Jiang Z, Chan J, Bartholomeu DC, Lauw F, Hall JP, Barber GN, Gazzinelli RT, Fitzgerald KA, Golenbock DT. Sharma S, et al. Among authors: fitzgerald ka. Immunity. 2011 Aug 26;35(2):194-207. doi: 10.1016/j.immuni.2011.05.016. Epub 2011 Aug 4. Immunity. 2011. PMID: 21820332 Free PMC article.
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M. Shimada K, et al. Among authors: fitzgerald ka. Immunity. 2012 Mar 23;36(3):401-14. doi: 10.1016/j.immuni.2012.01.009. Epub 2012 Feb 16. Immunity. 2012. PMID: 22342844 Free PMC article.
Regulation of inflammasome signaling.
Rathinam VA, Vanaja SK, Fitzgerald KA. Rathinam VA, et al. Among authors: fitzgerald ka. Nat Immunol. 2012 Mar 19;13(4):333-42. doi: 10.1038/ni.2237. Nat Immunol. 2012. PMID: 22430786 Free PMC article. Review.
357 results