Bastos Mde L - Search Results

1

Induction and activation of P-glycoprotein by dihydroxylated xanthones protect against the cytotoxicity of the P-glycoprotein substrate paraquat.

Silva R, Sousa E, Carmo H, Palmeira A, Barbosa DJ, Gameiro M, Pinto M, Bastos Mde L, Remião F. Silva R, et al. Among authors: bastos mde l. Arch Toxicol. 2014 Apr;88(4):937-51. doi: 10.1007/s00204-014-1193-y. Epub 2014 Jan 25. Arch Toxicol. 2014. PMID: 24464498

2

In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells.

Silva R, Carmo H, Dinis-Oliveira R, Cordeiro-da-Silva A, Lima SC, Carvalho F, Bastos Mde L, Remião F. Silva R, et al. Among authors: bastos mde l. Arch Toxicol. 2011 Apr;85(4):315-26. doi: 10.1007/s00204-010-0587-8. Epub 2010 Sep 21. Arch Toxicol. 2011. PMID: 20857089

3

Doxorubicin decreases paraquat accumulation and toxicity in Caco-2 cells.

Silva R, Carmo H, Vilas-Boas V, de Pinho PG, Dinis-Oliveira RJ, Carvalho F, Silva I, Correia-de-Sá P, Bastos Mde L, Remião F. Silva R, et al. Among authors: bastos mde l. Toxicol Lett. 2013 Feb 13;217(1):34-41. doi: 10.1016/j.toxlet.2012.11.028. Epub 2012 Dec 7. Toxicol Lett. 2013. PMID: 23220037

4

Mechanisms of P-gp inhibition and effects on membrane fluidity of a new rifampicin derivative, 1,8-dibenzoyl-rifampicin.

Vilas-Boas V, Silva R, Nunes C, Reis S, Ferreira L, Vieira C, Carvalho F, Bastos Mde L, Remião F. Vilas-Boas V, et al. Among authors: bastos mde l. Toxicol Lett. 2013 Jul 18;220(3):259-66. doi: 10.1016/j.toxlet.2013.05.005. Epub 2013 May 16. Toxicol Lett. 2013. PMID: 23685082

5

Development of novel rifampicin-derived P-glycoprotein activators/inducers. synthesis, in silico analysis and application in the RBE4 cell model, using paraquat as substrate.

Vilas-Boas V, Silva R, Palmeira A, Sousa E, Ferreira LM, Branco PS, Carvalho F, Bastos Mde L, Remião F. Vilas-Boas V, et al. Among authors: bastos mde l. PLoS One. 2013 Aug 26;8(8):e74425. doi: 10.1371/journal.pone.0074425. eCollection 2013. PLoS One. 2013. PMID: 23991219 Free PMC article.

6

The mixture of "ecstasy" and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations.

Barbosa DJ, Capela JP, Silva R, Vilas-Boas V, Ferreira LM, Branco PS, Fernandes E, Bastos Mde L, Carvalho F. Barbosa DJ, et al. Among authors: bastos mde l. Arch Toxicol. 2014 Feb;88(2):455-73. doi: 10.1007/s00204-013-1120-7. Epub 2013 Oct 8. Arch Toxicol. 2014. PMID: 24101030

7

Colchicine effect on P-glycoprotein expression and activity: in silico and in vitro studies.

Silva R, Carmo H, Vilas-Boas V, Barbosa DJ, Palmeira A, Sousa E, Carvalho F, Bastos Mde L, Remião F. Silva R, et al. Among authors: bastos mde l. Chem Biol Interact. 2014 Jul 25;218:50-62. doi: 10.1016/j.cbi.2014.04.009. Epub 2014 Apr 20. Chem Biol Interact. 2014. PMID: 24759273

8

P-glycoprotein induction in Caco-2 cells by newly synthetized thioxanthones prevents paraquat cytotoxicity.

Silva R, Palmeira A, Carmo H, Barbosa DJ, Gameiro M, Gomes A, Paiva AM, Sousa E, Pinto M, Bastos Mde L, Remião F. Silva R, et al. Among authors: bastos mde l. Arch Toxicol. 2015 Oct;89(10):1783-800. doi: 10.1007/s00204-014-1333-4. Epub 2014 Sep 19. Arch Toxicol. 2015. PMID: 25234084

9

Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.

Gameiro M, Silva R, Rocha-Pereira C, Carmo H, Carvalho F, Bastos ML, Remião F. Gameiro M, et al. Molecules. 2017 Apr 8;22(4):600. doi: 10.3390/molecules22040600. Molecules. 2017. PMID: 28397762 Free PMC article. Review.

10

P-glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: ex vivo and in vivo studies.

Rocha-Pereira C, Ghanem CI, Silva R, Casanova AG, Duarte-Araújo M, Gonçalves-Monteiro S, Sousa E, Bastos ML, Remião F. Rocha-Pereira C, et al. Toxicol Appl Pharmacol. 2020 Jan 1;386:114832. doi: 10.1016/j.taap.2019.114832. Epub 2019 Nov 19. Toxicol Appl Pharmacol. 2020. PMID: 31756430

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