Carson MW - Search Results

1

Glucocorticoid receptor modulators informed by crystallography lead to a new rationale for receptor selectivity, function, and implications for structure-based design.

Carson MW, Luz JG, Suen C, Montrose C, Zink R, Ruan X, Cheng C, Cole H, Adrian MD, Kohlman DT, Mabry T, Snyder N, Condon B, Maletic M, Clawson D, Pustilnik A, Coghlan MJ. Carson MW, et al. J Med Chem. 2014 Feb 13;57(3):849-60. doi: 10.1021/jm401616g. Epub 2014 Feb 4. J Med Chem. 2014. PMID: 24446728

2

Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.

Luz JG, Carson MW, Condon B, Clawson D, Pustilnik A, Kohlman DT, Barr RJ, Bean JS, Dill MJ, Sindelar DK, Maletic M, Coghlan MJ. Luz JG, et al. Among authors: carson mw. J Med Chem. 2015 Aug 27;58(16):6607-18. doi: 10.1021/acs.jmedchem.5b00736. Epub 2015 Aug 7. J Med Chem. 2015. PMID: 26218343

3

An intra/intermolecular suzuki sequence to benzopyridyloxepines containing geometrically pure exocyclic tetrasubstituted alkenes.

Carson MW, Giese MW, Coghlan MJ. Carson MW, et al. Org Lett. 2008 Jul 3;10(13):2701-4. doi: 10.1021/ol800834q. Epub 2008 Jun 7. Org Lett. 2008. PMID: 18537249

4

Cyclocarbopalladation of alkynes: a stereoselective method for preparing dibenzoxapine containing tetrasubstituted exocyclic alkenes.

Yu H, Richey RN, Carson MW, Coghlan MJ. Yu H, et al. Among authors: carson mw. Org Lett. 2006 Apr 13;8(8):1685-8. doi: 10.1021/ol060289a. Org Lett. 2006. PMID: 16597141

5

HDX reveals unique fragment ligands for the vitamin D receptor.

Carson MW, Zhang J, Chalmers MJ, Bocchinfuso WP, Holifield KD, Masquelin T, Stites RE, Stayrook KR, Griffin PR, Dodge JA. Carson MW, et al. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3459-63. doi: 10.1016/j.bmcl.2014.05.070. Epub 2014 May 29. Bioorg Med Chem Lett. 2014. PMID: 24974344

6

N-(carboxymethyl)-N-[3,5-bis(decyloxy)-phenyl]glycine (Ro 23-9358): a potent inhibitor of secretory phospholipases A2 with antiinflammatory activity.

LeMahieu RA, Carson M, Han RJ, Madison VS, Hope WC, Chen T, Morgan DW, Hendrickson HS. LeMahieu RA, et al. J Med Chem. 1993 Oct 1;36(20):3029-31. doi: 10.1021/jm00072a025. J Med Chem. 1993. PMID: 8411020 No abstract available.

7

(E)-3-(4-Oxo-4H-quinazolin-3-yl)-2-propenoic acids, a new series of antiallergy agents.

LeMahieu RA, Carson M, Nason WC, Parrish DR, Welton AF, Baruth HW, Yaremko B. LeMahieu RA, et al. J Med Chem. 1983 Mar;26(3):420-5. doi: 10.1021/jm00357a018. J Med Chem. 1983. PMID: 6827560

8

Pyrido[2,1-b]quinazolinecarboxylic acids as orally active antiallergy agents.

Tilley JW, LeMahieu RA, Carson M, Kierstead RW, Baruth HW, Yaremko B. Tilley JW, et al. J Med Chem. 1980 Jan;23(1):92-5. doi: 10.1021/jm00175a020. J Med Chem. 1980. PMID: 7359521

9

Substituted (aryloxy)alkanoic acids as antagonists of slow-reacting substance of anaphylaxis.

LeMahieu RA, Carson M, Han RJ, Nason WC, O'Donnell M, Brown DL, Crowley HJ, Welton AF. LeMahieu RA, et al. J Med Chem. 1987 Jan;30(1):173-8. doi: 10.1021/jm00384a029. J Med Chem. 1987. PMID: 3027332

10

Synthesis and antiallergy activity of 5-oxo-5H-thiazolo[2,3-b]quinazolinecarboxylic acids.

LeMahieu RA, Carson M, Welton AF, Baruth HW, Yaremko B. LeMahieu RA, et al. J Med Chem. 1983 Jan;26(1):107-10. doi: 10.1021/jm00355a022. J Med Chem. 1983. PMID: 6827522 No abstract available.

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