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Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the β' subunit of RNA polymerase.
Song T, Park Y, Shamputa IC, Seo S, Lee SY, Jeon HS, Choi H, Lee M, Glynne RJ, Barnes SW, Walker JR, Batalov S, Yusim K, Feng S, Tung CS, Theiler J, Via LE, Boshoff HI, Murakami KS, Korber B, Barry CE 3rd, Cho SN. Song T, et al. Mol Microbiol. 2014 Mar;91(6):1106-19. doi: 10.1111/mmi.12520. Epub 2014 Feb 26. Mol Microbiol. 2014. PMID: 24417450 Free PMC article.
Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis.
Xie YL, Chakravorty S, Armstrong DT, Hall SL, Via LE, Song T, Yuan X, Mo X, Zhu H, Xu P, Gao Q, Lee M, Lee J, Smith LE, Chen RY, Joh JS, Cho Y, Liu X, Ruan X, Liang L, Dharan N, Cho SN, Barry CE 3rd, Ellner JJ, Dorman SE, Alland D. Xie YL, et al. Among authors: song t. N Engl J Med. 2017 Sep 14;377(11):1043-1054. doi: 10.1056/NEJMoa1614915. N Engl J Med. 2017. PMID: 28902596 Free PMC article.
Linezolid for treatment of chronic extensively drug-resistant tuberculosis.
Lee M, Lee J, Carroll MW, Choi H, Min S, Song T, Via LE, Goldfeder LC, Kang E, Jin B, Park H, Kwak H, Kim H, Jeon HS, Jeong I, Joh JS, Chen RY, Olivier KN, Shaw PA, Follmann D, Song SD, Lee JK, Lee D, Kim CT, Dartois V, Park SK, Cho SN, Barry CE 3rd. Lee M, et al. Among authors: song t, song sd. N Engl J Med. 2012 Oct 18;367(16):1508-18. doi: 10.1056/NEJMoa1201964. N Engl J Med. 2012. PMID: 23075177 Free PMC article. Clinical Trial.
Linezolid for XDR-TB--Final Study Outcomes.
Lee M, Cho SN, Barry CE 3rd, Song T, Kim Y, Jeong I. Lee M, et al. Among authors: song t. N Engl J Med. 2015 Jul 16;373(3):290-1. doi: 10.1056/NEJMc1500286. N Engl J Med. 2015. PMID: 26176401 Free PMC article. No abstract available.
The association between sterilizing activity and drug distribution into tuberculosis lesions.
Prideaux B, Via LE, Zimmerman MD, Eum S, Sarathy J, O'Brien P, Chen C, Kaya F, Weiner DM, Chen PY, Song T, Lee M, Shim TS, Cho JS, Kim W, Cho SN, Olivier KN, Barry CE 3rd, Dartois V. Prideaux B, et al. Among authors: song t. Nat Med. 2015 Oct;21(10):1223-7. doi: 10.1038/nm.3937. Epub 2015 Sep 7. Nat Med. 2015. PMID: 26343800 Free PMC article.
Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis.
Song T, Lee M, Jeon HS, Park Y, Dodd LE, Dartois V, Follman D, Wang J, Cai Y, Goldfeder LC, Olivier KN, Xie Y, Via LE, Cho SN, Barry CE 3rd, Chen RY. Song T, et al. EBioMedicine. 2015 Oct 9;2(11):1627-33. doi: 10.1016/j.ebiom.2015.09.051. eCollection 2015 Nov. EBioMedicine. 2015. PMID: 26870788 Free PMC article. Clinical Trial.
Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.
Malherbe ST, Shenai S, Ronacher K, Loxton AG, Dolganov G, Kriel M, Van T, Chen RY, Warwick J, Via LE, Song T, Lee M, Schoolnik G, Tromp G, Alland D, Barry CE 3rd, Winter J, Walzl G; Catalysis TB–Biomarker Consortium; Lucas L, Spuy GV, Stanley K, Thiart L, Smith B, Du Plessis N, Beltran CG, Maasdorp E, Ellmann A, Choi H, Joh J, Dodd LE, Allwood B, Koegelenberg C, Vorster M, Griffith-Richards S. Malherbe ST, et al. Among authors: song t. Nat Med. 2016 Oct;22(10):1094-1100. doi: 10.1038/nm.4177. Epub 2016 Sep 5. Nat Med. 2016. PMID: 27595324 Free PMC article.
4,655 results