Abstract
Prolonged use of linezolid was temporally and mechanistically associated with rhabdomyolysis in a patient being treated for extensively drug-resistant tuberculosis. Careful laboratory monitoring of such subjects is important during prolonged linezolid therapy.
Publication types
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Case Reports
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Clinical Trial, Phase II
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Randomized Controlled Trial
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Research Support, N.I.H., Intramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetamides / administration & dosage*
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Acetamides / adverse effects*
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Adult
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Antitubercular Agents / administration & dosage*
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Antitubercular Agents / adverse effects*
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Extensively Drug-Resistant Tuberculosis / drug therapy*
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Humans
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Linezolid
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Male
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Oxazolidinones / administration & dosage*
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Oxazolidinones / adverse effects*
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Rhabdomyolysis / chemically induced*
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Rhabdomyolysis / pathology
Substances
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Acetamides
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Antitubercular Agents
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Oxazolidinones
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Linezolid