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Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.
Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C. Liszewski MK, et al. Among authors: arstila tp. Immunity. 2013 Dec 12;39(6):1143-57. doi: 10.1016/j.immuni.2013.10.018. Epub 2013 Dec 5. Immunity. 2013. PMID: 24315997 Free PMC article.
Impaired intestinal tolerance in the absence of a functional complement system.
Pekkarinen PT, Vaali K, Jarva H, Kekäläinen E, Hetemäki I, Junnikkala S, Helminen M, Vaarala O, Meri S, Arstila TP. Pekkarinen PT, et al. Among authors: arstila tp. J Allergy Clin Immunol. 2013 Apr;131(4):1167-75. doi: 10.1016/j.jaci.2012.09.004. Epub 2012 Oct 23. J Allergy Clin Immunol. 2013. PMID: 23098807
Dysregulation of adaptive immune responses in complement C3-deficient patients.
Pekkarinen PT, Heikkilä N, Kisand K, Peterson P, Botto M, Daha MR, Drouet C, Isaac L, Helminen M, Haahtela T, Meri S, Jarva H, Arstila TP. Pekkarinen PT, et al. Among authors: arstila tp. Eur J Immunol. 2015 Mar;45(3):915-21. doi: 10.1002/eji.201444948. Epub 2015 Jan 19. Eur J Immunol. 2015. PMID: 25446578 Free article. Clinical Trial.
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