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PEGylated drugs in rheumatology--why develop them and do they work?
McDonnell T, Ioannou Y, Rahman A. McDonnell T, et al. Among authors: ioannou y. Rheumatology (Oxford). 2014 Mar;53(3):391-6. doi: 10.1093/rheumatology/ket278. Epub 2013 Aug 20. Rheumatology (Oxford). 2014. PMID: 23962623 Free PMC article. Review.
Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis.
Pericleous C, Ruiz-Limón P, Romay-Penabad Z, Marín AC, Garza-Garcia A, Murfitt L, Driscoll PC, Latchman DS, Isenberg DA, Giles I, Ioannou Y, Rahman A, Pierangeli SS. Pericleous C, et al. Among authors: ioannou y. Rheumatology (Oxford). 2015 Apr;54(4):722-7. doi: 10.1093/rheumatology/keu360. Epub 2014 Sep 30. Rheumatology (Oxford). 2015. PMID: 25273993 Free PMC article.
PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome.
McDonnell TCR, Willis R, Pericleous C, Ripoll VM, Giles IP, Isenberg DA, Brasier AR, Gonzalez EB, Papalardo E, Romay-Penabad Z, Jamaluddin M, Ioannou Y, Rahman A. McDonnell TCR, et al. Among authors: ioannou y. Front Immunol. 2018 Oct 22;9:2413. doi: 10.3389/fimmu.2018.02413. eCollection 2018. Front Immunol. 2018. PMID: 30405613 Free PMC article.
Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome.
Pericleous C, Ferreira I, Borghi O, Pregnolato F, McDonnell T, Garza-Garcia A, Driscoll P, Pierangeli S, Isenberg D, Ioannou Y, Giles I, Meroni PL, Rahman A. Pericleous C, et al. Among authors: ioannou y. PLoS One. 2016 Jun 2;11(6):e0156407. doi: 10.1371/journal.pone.0156407. eCollection 2016. PLoS One. 2016. PMID: 27253369 Free PMC article.
193 results