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Novel broad-spectrum bis-(imidazolinylindole) derivatives with potent antibacterial activities against antibiotic-resistant strains.
Panchal RG, Ulrich RL, Lane D, Butler MM, Houseweart C, Opperman T, Williams JD, Peet NP, Moir DT, Nguyen T, Gussio R, Bowlin T, Bavari S. Panchal RG, et al. Antimicrob Agents Chemother. 2009 Oct;53(10):4283-91. doi: 10.1128/AAC.01709-08. Epub 2009 Jul 27. Antimicrob Agents Chemother. 2009. PMID: 19635954 Free PMC article.
Anthrax biosensor, protective antigen ion channel asymmetric blockade.
Halverson KM, Panchal RG, Nguyen TL, Gussio R, Little SF, Misakian M, Bavari S, Kasianowicz JJ. Halverson KM, et al. Among authors: nguyen tl. J Biol Chem. 2005 Oct 7;280(40):34056-62. doi: 10.1074/jbc.M507928200. Epub 2005 Aug 8. J Biol Chem. 2005. PMID: 16087661 Free article.
Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
Burnett JC, Ruthel G, Stegmann CM, Panchal RG, Nguyen TL, Hermone AR, Stafford RG, Lane DJ, Kenny TA, McGrath CF, Wipf P, Stahl AM, Schmidt JJ, Gussio R, Brunger AT, Bavari S. Burnett JC, et al. Among authors: nguyen tl. J Biol Chem. 2007 Feb 16;282(7):5004-5014. doi: 10.1074/jbc.M608166200. Epub 2006 Nov 8. J Biol Chem. 2007. PMID: 17092934 Free article.
Association of ebola virus matrix protein VP40 with microtubules.
Ruthel G, Demmin GL, Kallstrom G, Javid MP, Badie SS, Will AB, Nelle T, Schokman R, Nguyen TL, Carra JH, Bavari S, Aman MJ. Ruthel G, et al. Among authors: nguyen tl. J Virol. 2005 Apr;79(8):4709-19. doi: 10.1128/JVI.79.8.4709-4719.2005. J Virol. 2005. PMID: 15795257 Free PMC article.
Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity.
Burnett JC, Schmidt JJ, Stafford RG, Panchal RG, Nguyen TL, Hermone AR, Vennerstrom JL, McGrath CF, Lane DJ, Sausville EA, Zaharevitz DW, Gussio R, Bavari S. Burnett JC, et al. Among authors: nguyen tl. Biochem Biophys Res Commun. 2003 Oct 10;310(1):84-93. doi: 10.1016/j.bbrc.2003.08.112. Biochem Biophys Res Commun. 2003. PMID: 14511652
711 results