Paraoxonase 1 protects against protein N-homocysteinylation in humans.
Perla-Kaján J, Jakubowski H.
Perla-Kaján J, et al. Among authors: jakubowski h.
FASEB J. 2010 Mar;24(3):931-6. doi: 10.1096/fj.09-144410. Epub 2009 Oct 30.
FASEB J. 2010.
PMID: 19880629
These findings provide evidence that the Hcy-thiolactonase activity of PON1 is a determinant of plasma N-Hcy-protein levels and that Hcy-thiolactonase/PON1 protects proteins against N-homocysteinylation in vivo, a novel mechanism likely to contribute to atheroprotective roles of …
These findings provide evidence that the Hcy-thiolactonase activity of PON1 is a determinant of plasma N-Hcy-protein levels and that Hcy-thi …