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In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE).
Perdona' E, Costantini VJ, Tessari M, Martinelli P, Carignani C, Valerio E, Mok MH, Zonzini L, Visentini F, Gianotti M, Gordon L, Rocheville M, Corsi M, Capelli AM. Perdona' E, et al. Among authors: corsi m. Neuropharmacology. 2011 Oct-Nov;61(5-6):957-66. doi: 10.1016/j.neuropharm.2011.06.024. Epub 2011 Jul 5. Neuropharmacology. 2011. PMID: 21756923
Azabicyclo[3.1.0]hexane-1-carbohydrazides as potent and selective GHSR1a ligands presenting a specific in vivo behavior.
Sabbatini FM, Melotto S, Bernasconi G, Bromidge SM, D'Adamo L, Rinaldi M, Savoia C, Mundi C, Di Francesco C, Zonzini L, Costantini VJ, Perini B, Valerio E, Pozzan A, Perdonà E, Visentini F, Corsi M, Di Fabio R. Sabbatini FM, et al. Among authors: corsi m. ChemMedChem. 2011 Nov 4;6(11):1981-5. doi: 10.1002/cmdc.201100285. Epub 2011 Aug 10. ChemMedChem. 2011. PMID: 21834097 No abstract available.
Discovery process and characterization of novel carbohydrazide derivatives as potent and selective GHSR1a antagonists.
Sabbatini FM, Di Fabio R, Corsi M, Cavanni P, Bromidge SM, St-Denis Y, D'Adamo L, Contini S, Rinaldi M, Guery S, Savoia C, Mundi C, Perini B, Carpenter AJ, Dal Forno G, Faggioni F, Tessari M, Pavone F, Di Francesco C, Buson A, Mattioli M, Perdona' E, Melotto S. Sabbatini FM, et al. Among authors: corsi m. ChemMedChem. 2010 Sep 3;5(9):1450-5. doi: 10.1002/cmdc.201000185. ChemMedChem. 2010. PMID: 20593439 No abstract available.
Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats.
Piccoli L, Micioni Di Bonaventura MV, Cifani C, Costantini VJ, Massagrande M, Montanari D, Martinelli P, Antolini M, Ciccocioppo R, Massi M, Merlo-Pich E, Di Fabio R, Corsi M. Piccoli L, et al. Among authors: corsi m. Neuropsychopharmacology. 2012 Aug;37(9):1999-2011. doi: 10.1038/npp.2012.48. Epub 2012 May 9. Neuropsychopharmacology. 2012. PMID: 22569505 Free PMC article.
Synthesis and pharmacological characterization of constrained analogues of Vestipitant as in vitro potent and orally active NK(1) receptor antagonists.
Sabbatini FM, Di Fabio R, Griffante C, Pentassuglia G, Zonzini L, Melotto S, Alvaro G, Capelli AM, Pippo L, Perdona' E, St Denis Y, Costa S, Corsi M. Sabbatini FM, et al. Among authors: corsi m. Bioorg Med Chem Lett. 2010 Jan 15;20(2):623-7. doi: 10.1016/j.bmcl.2009.11.078. Epub 2009 Nov 20. Bioorg Med Chem Lett. 2010. PMID: 19963378
541 results