Azabicyclo[3.1.0]hexane-1-carbohydrazides as potent and selective GHSR1a ligands presenting a specific in vivo behavior

MeSH terms

• Animals
• Appetite Stimulants / chemistry*
• Appetite Stimulants / pharmacokinetics
• Appetite Stimulants / pharmacology
• Body Weight / drug effects*
• Circular Dichroism
• Eating / drug effects*
• Female
• Ghrelin / antagonists & inhibitors*
• Ghrelin / metabolism
• Hydrazines / chemistry*
• Hydrazines / pharmacokinetics
• Hydrazines / pharmacology*
• Ligands
• Molecular Structure
• Rats
• Rats, Sprague-Dawley
• Receptors, Ghrelin* / antagonists & inhibitors
• Structure-Activity Relationship