Bohlen H - Search Results

1

Automated patch clamp on mESC-derived cardiomyocytes for cardiotoxicity prediction.

Stoelzle S, Haythornthwaite A, Kettenhofen R, Kolossov E, Bohlen H, George M, Brüggemann A, Fertig N. Stoelzle S, et al. Among authors: bohlen h. J Biomol Screen. 2011 Sep;16(8):910-6. doi: 10.1177/1087057111413924. Epub 2011 Jul 20. J Biomol Screen. 2011. PMID: 21775699

2

Minimized cell usage for stem cell-derived and primary cells on an automated patch clamp system.

Becker N, Stoelzle S, Göpel S, Guinot D, Mumm P, Haarmann C, Malan D, Bohlen H, Kossolov E, Kettenhofen R, George M, Fertig N, Brüggemann A. Becker N, et al. Among authors: bohlen h. J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):82-7. doi: 10.1016/j.vascn.2013.03.009. Epub 2013 Apr 6. J Pharmacol Toxicol Methods. 2013. PMID: 23567076 Free article.

3

Preclinical assessment of cardiac toxicity.

Kettenhofen R, Bohlen H. Kettenhofen R, et al. Among authors: bohlen h. Drug Discov Today. 2008 Aug;13(15-16):702-7. doi: 10.1016/j.drudis.2008.06.011. Epub 2008 Jul 24. Drug Discov Today. 2008. PMID: 18602016 Review.

4

Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation.

Rehnelt S, Malan D, Juhasz K, Wolters B, Doerr L, Beckler M, Kettenhofen R, Bohlen H, Bruegmann T, Sasse P. Rehnelt S, et al. Among authors: bohlen h. Int J Mol Sci. 2017 Dec 6;18(12):2634. doi: 10.3390/ijms18122634. Int J Mol Sci. 2017. PMID: 29211031 Free PMC article.

5

Dynamic monitoring of beating periodicity of stem cell-derived cardiomyocytes as a predictive tool for preclinical safety assessment.

Abassi YA, Xi B, Li N, Ouyang W, Seiler A, Watzele M, Kettenhofen R, Bohlen H, Ehlich A, Kolossov E, Wang X, Xu X. Abassi YA, et al. Among authors: bohlen h. Br J Pharmacol. 2012 Mar;165(5):1424-41. doi: 10.1111/j.1476-5381.2011.01623.x. Br J Pharmacol. 2012. PMID: 21838757 Free PMC article.

6

An impedance-based approach using human iPSC-derived cardiomyocytes significantly improves in vitro prediction of in vivo cardiotox liabilities.

Koci B, Luerman G, Duenbostell A, Kettenhofen R, Bohlen H, Coyle L, Knight B, Ku W, Volberg W, Woska JR Jr, Brown MP. Koci B, et al. Among authors: bohlen h. Toxicol Appl Pharmacol. 2017 Aug 15;329:121-127. doi: 10.1016/j.taap.2017.05.023. Epub 2017 May 22. Toxicol Appl Pharmacol. 2017. PMID: 28546047

7

Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium.

Kolossov E, Bostani T, Roell W, Breitbach M, Pillekamp F, Nygren JM, Sasse P, Rubenchik O, Fries JW, Wenzel D, Geisen C, Xia Y, Lu Z, Duan Y, Kettenhofen R, Jovinge S, Bloch W, Bohlen H, Welz A, Hescheler J, Jacobsen SE, Fleischmann BK. Kolossov E, et al. Among authors: bohlen h. J Exp Med. 2006 Oct 2;203(10):2315-27. doi: 10.1084/jem.20061469. Epub 2006 Sep 5. J Exp Med. 2006. PMID: 16954371 Free PMC article.

8

Identification and characterization of embryonic stem cell-derived pacemaker and atrial cardiomyocytes.

Kolossov E, Lu Z, Drobinskaya I, Gassanov N, Duan Y, Sauer H, Manzke O, Bloch W, Bohlen H, Hescheler J, Fleischmann BK. Kolossov E, et al. Among authors: bohlen h. FASEB J. 2005 Apr;19(6):577-9. doi: 10.1096/fj.03-1451fje. Epub 2005 Jan 19. FASEB J. 2005. PMID: 15659535

9

Correction: Rehnelt et al. Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation. Int. J. Mol. Sci. 2017, 18, 2634.

Rehnelt S, Malan D, Juhasz K, Wolters B, Doerr L, Beckler M, Kettenhofen R, Bohlen H, Bruegmann T, Sasse P. Rehnelt S, et al. Among authors: bohlen h. Int J Mol Sci. 2021 May 25;22(11):5562. doi: 10.3390/ijms22115562. Int J Mol Sci. 2021. PMID: 34070702 Free PMC article.

10

Functional characteristics of ES cell-derived cardiac precursor cells identified by tissue-specific expression of the green fluorescent protein.

Kolossov E, Fleischmann BK, Liu Q, Bloch W, Viatchenko-Karpinski S, Manzke O, Ji GJ, Bohlen H, Addicks K, Hescheler J. Kolossov E, et al. Among authors: bohlen h. J Cell Biol. 1998 Dec 28;143(7):2045-56. doi: 10.1083/jcb.143.7.2045. J Cell Biol. 1998. PMID: 9864374 Free PMC article.

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