Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.
Guo L, Bi W, Wang X, Xu W, Yan R, Zhang Y, Zhao K, Li Y, Zhang M, Cai X, Jiang S, Xie Y, Zhou Q, Lu L, Dang B.
Guo L, et al. Among authors: xu w.
Cell Res. 2021 Jan;31(1):98-100. doi: 10.1038/s41422-020-00438-w. Epub 2020 Nov 11.
Cell Res. 2021.
PMID: 33177651
Free PMC article.
No abstract available.