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Page 1
Efficient parallel synthesis of macrocyclic peptidomimetics.
Marsault E, Hoveyda HR, Gagnon R, Peterson ML, Vézina M, Saint-Louis C, Landry A, Pinault JF, Ouellet L, Beauchemin S, Beaubien S, Mathieu A, Benakli K, Wang Z, Brassard M, Lonergan D, Bilodeau F, Ramaseshan M, Fortin N, Lan R, Li S, Galaud F, Plourde V, Champagne M, Doucet A, Bhérer P, Gauthier M, Olsen G, Villeneuve G, Bhat S, Foucher L, Fortin D, Peng X, Bernard S, Drouin A, Déziel R, Berthiaume G, Dory YL, Fraser GL, Deslongchamps P. Marsault E, et al. Among authors: ramaseshan m. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4731-5. doi: 10.1016/j.bmcl.2008.06.085. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18640834
Discovery of a new class of macrocyclic antagonists to the human motilin receptor.
Marsault E, Hoveyda HR, Peterson ML, Saint-Louis C, Landry A, Vézina M, Ouellet L, Wang Z, Ramaseshan M, Beaubien S, Benakli K, Beauchemin S, Déziel R, Peeters T, Fraser GL. Marsault E, et al. Among authors: ramaseshan m. J Med Chem. 2006 Nov 30;49(24):7190-7. doi: 10.1021/jm0606600. J Med Chem. 2006. PMID: 17125271
Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic.
Hoveyda HR, Marsault E, Gagnon R, Mathieu AP, Vézina M, Landry A, Wang Z, Benakli K, Beaubien S, Saint-Louis C, Brassard M, Pinault JF, Ouellet L, Bhat S, Ramaseshan M, Peng X, Foucher L, Beauchemin S, Bhérer P, Veber DF, Peterson ML, Fraser GL. Hoveyda HR, et al. Among authors: ramaseshan m. J Med Chem. 2011 Dec 22;54(24):8305-20. doi: 10.1021/jm2007062. Epub 2011 Nov 22. J Med Chem. 2011. PMID: 22106937
High throughput solid phase parallel synthesis of macrocyclic peptidomimetics.
Marsault E, Hoveyda HR, Peterson ML, Gagnon R, Vézina M, Pinault JF, Landry A, Saint-Louis C, Ouellet LG, Beauchemin S, Benakli K, Beaubien S, Brassard M, Wang Z, Champagne M, Galaud F, Fortin N, Fortin D, Plourde V, Ramaseshan M, Bhat S, Bilodeau F, Lonergan D, Lan R, Li S, Berthiaume G, Foucher L, Peng X, Dory Y, Deslongchamps P. Marsault E, et al. Among authors: ramaseshan m. Adv Exp Med Biol. 2009;611:15-6. doi: 10.1007/978-0-387-73657-0_7. Adv Exp Med Biol. 2009. PMID: 19400074 No abstract available.
Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.
Boehm M, Beaumont K, Jones R, Kalgutkar AS, Zhang L, Atkinson K, Bai G, Brown JA, Eng H, Goetz GH, Holder BR, Khunte B, Lazzaro S, Limberakis C, Ryu S, Shapiro MJ, Tylaska L, Yan J, Turner R, Leung SSF, Ramaseshan M, Price DA, Liras S, Jacobson MP, Earp DJ, Lokey RS, Mathiowetz AM, Menhaji-Klotz E. Boehm M, et al. Among authors: ramaseshan m. J Med Chem. 2017 Dec 14;60(23):9653-9663. doi: 10.1021/acs.jmedchem.7b01028. Epub 2017 Oct 30. J Med Chem. 2017. PMID: 29045152 Free article.