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Page 1
Efficient parallel synthesis of macrocyclic peptidomimetics.
Marsault E, Hoveyda HR, Gagnon R, Peterson ML, Vézina M, Saint-Louis C, Landry A, Pinault JF, Ouellet L, Beauchemin S, Beaubien S, Mathieu A, Benakli K, Wang Z, Brassard M, Lonergan D, Bilodeau F, Ramaseshan M, Fortin N, Lan R, Li S, Galaud F, Plourde V, Champagne M, Doucet A, Bhérer P, Gauthier M, Olsen G, Villeneuve G, Bhat S, Foucher L, Fortin D, Peng X, Bernard S, Drouin A, Déziel R, Berthiaume G, Dory YL, Fraser GL, Deslongchamps P. Marsault E, et al. Among authors: deziel r. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4731-5. doi: 10.1016/j.bmcl.2008.06.085. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18640834
Discovery of a new class of macrocyclic antagonists to the human motilin receptor.
Marsault E, Hoveyda HR, Peterson ML, Saint-Louis C, Landry A, Vézina M, Ouellet L, Wang Z, Ramaseshan M, Beaubien S, Benakli K, Beauchemin S, Déziel R, Peeters T, Fraser GL. Marsault E, et al. Among authors: deziel r. J Med Chem. 2006 Nov 30;49(24):7190-7. doi: 10.1021/jm0606600. J Med Chem. 2006. PMID: 17125271
Optimization and determination of the absolute configuration of a series of potent inhibitors of human papillomavirus type-11 E1-E2 protein-protein interaction: a combined medicinal chemistry, NMR and computational chemistry approach.
Goudreau N, Cameron DR, Déziel R, Haché B, Jakalian A, Malenfant E, Naud J, Ogilvie WW, O'meara J, White PW, Yoakim C. Goudreau N, et al. Among authors: deziel r. Bioorg Med Chem. 2007 Apr 1;15(7):2690-700. doi: 10.1016/j.bmc.2007.01.036. Epub 2007 Jan 24. Bioorg Med Chem. 2007. PMID: 17306550
N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).
Allan M, Manku S, Therrien E, Nguyen N, Styhler S, Robert MF, Goulet AC, Petschner AJ, Rahil G, Robert Macleod A, Déziel R, Besterman JM, Nguyen H, Wahhab A. Allan M, et al. Among authors: deziel r. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1218-23. doi: 10.1016/j.bmcl.2008.12.075. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19131248
Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases.
Claridge S, Raeppel F, Granger MC, Bernstein N, Saavedra O, Zhan L, Llewellyn D, Wahhab A, Deziel R, Rahil J, Beaulieu N, Nguyen H, Dupont I, Barsalou A, Beaulieu C, Chute I, Gravel S, Robert MF, Lefebvre S, Dubay M, Pascal R, Gillespie J, Jin Z, Wang J, Besterman JM, MacLeod AR, Vaisburg A. Claridge S, et al. Among authors: deziel r. Bioorg Med Chem Lett. 2008 May 1;18(9):2793-8. doi: 10.1016/j.bmcl.2008.04.009. Epub 2008 Apr 9. Bioorg Med Chem Lett. 2008. PMID: 18434145
N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: a novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors.
Mannion M, Raeppel S, Claridge S, Zhou N, Saavedra O, Isakovic L, Zhan L, Gaudette F, Raeppel F, Déziel R, Beaulieu N, Nguyen H, Chute I, Beaulieu C, Dupont I, Robert MF, Lefebvre S, Dubay M, Rahil J, Wang J, Ste-Croix H, Robert Macleod A, Besterman JM, Vaisburg A. Mannion M, et al. Among authors: deziel r. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6552-6. doi: 10.1016/j.bmcl.2009.10.040. Epub 2009 Oct 13. Bioorg Med Chem Lett. 2009. PMID: 19854051
Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors.
Smil DV, Manku S, Chantigny YA, Leit S, Wahhab A, Yan TP, Fournel M, Maroun C, Li Z, Lemieux AM, Nicolescu A, Rahil J, Lefebvre S, Panetta A, Besterman JM, Déziel R. Smil DV, et al. Among authors: deziel r. Bioorg Med Chem Lett. 2009 Feb 1;19(3):688-92. doi: 10.1016/j.bmcl.2008.12.045. Epub 2008 Dec 14. Bioorg Med Chem Lett. 2009. PMID: 19111466
Sulfamides as novel histone deacetylase inhibitors.
Wahhab A, Smil D, Ajamian A, Allan M, Chantigny Y, Therrien E, Nguyen N, Manku S, Leit S, Rahil J, Petschner AJ, Lu AH, Nicolescu A, Lefebvre S, Montcalm S, Fournel M, Yan TP, Li Z, Besterman JM, Déziel R. Wahhab A, et al. Among authors: deziel r. Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. doi: 10.1016/j.bmcl.2008.11.081. Epub 2008 Nov 27. Bioorg Med Chem Lett. 2009. PMID: 19084395
Identification of a novel series of potent RON receptor tyrosine kinase inhibitors.
Raeppel S, Gaudette F, Mannion M, Claridge S, Saavedra O, Isakovic L, Déziel R, Beaulieu N, Beaulieu C, Dupont I, Nguyen H, Wang J, Macleod AR, Maroun C, Besterman JM, Vaisburg A. Raeppel S, et al. Among authors: deziel r. Bioorg Med Chem Lett. 2010 May 1;20(9):2745-9. doi: 10.1016/j.bmcl.2010.03.073. Epub 2010 Mar 19. Bioorg Med Chem Lett. 2010. PMID: 20363625
40 results