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Inhibition and dispersion of proteobacterial biofilms.
Richards JJ, Huigens Iii RW, Ballard TE, Basso A, Cavanagh J, Melander C. Richards JJ, et al. Among authors: huigens iii rw. Chem Commun (Camb). 2008 Apr 14;(14):1698-700. doi: 10.1039/b719802g. Epub 2008 Feb 8. Chem Commun (Camb). 2008. PMID: 18368169
First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival.
Guijarro MV, Kellish PC, Dib PE, Paciaroni NG, Nawab A, Andring J, Kulemina L, Borrero NV, Modenutti C, Feely M, Nasri E, Seifert RP, Luo X, Bennett RL, Shabashvili D, Licht JD, McKenna R, Roitberg A, Huigens RW 3rd, Kaye FJ, Zajac-Kaye M. Guijarro MV, et al. JCI Insight. 2023 Apr 25;8(10):e158798. doi: 10.1172/jci.insight.158798. JCI Insight. 2023. PMID: 37097751 Free PMC article.