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Inhibition and dispersion of proteobacterial biofilms.
Chem Commun (Camb). 2008 Apr 14;(14):1698-700. doi: 10.1039/b719802g. Epub 2008 Feb 8.
Chem Commun (Camb). 2008.
PMID: 18368169
Eradicating Bacterial Biofilms with Natural Products and Their Inspired Analogues that Operate Through Unique Mechanisms.
Garrison AT, Huigens Iii RW.
Garrison AT, et al. Among authors: huigens iii rw.
Curr Top Med Chem. 2016 Dec 14. Online ahead of print.
Curr Top Med Chem. 2016.
PMID: 27966398
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Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria.
Garrison AT, Abouelhassan Y, Yang H, Yousaf HH, Nguyen TJ, Huigens Iii RW.
Garrison AT, et al. Among authors: huigens iii rw.
Medchemcomm. 2016 Jul 27;8(4):720-724. doi: 10.1039/c6md00381h. eCollection 2017 Apr 1.
Medchemcomm. 2016.
PMID: 30108790
Free PMC article.
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Transcript Profiling of Nitroxoline-Treated Biofilms Shows Rapid Up-regulation of Iron Acquisition Gene Clusters.
Liu K, Abouelhassan Y, Zhang Y, Jin S, Huigens Iii RW.
Liu K, et al. Among authors: huigens iii rw.
ACS Infect Dis. 2022 Aug 12;8(8):1594-1605. doi: 10.1021/acsinfecdis.2c00206. Epub 2022 Jul 13.
ACS Infect Dis. 2022.
PMID: 35830188
Free PMC article.
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Design, synthesis and biological evaluation of a halogenated phenazine-erythromycin conjugate prodrug for antibacterial applications.
Yang H, Liu K, Jin S, Huigens Iii RW.
Yang H, et al. Among authors: huigens iii rw.
Org Biomol Chem. 2021 Feb 25;19(7):1483-1487. doi: 10.1039/d0ob02428g.
Org Biomol Chem. 2021.
PMID: 33521803
Free PMC article.
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Rapid kill assessment of an N-arylated NH125 analogue against drug-resistant microorganisms.
Abouelhassan Y, Zhang P, Ding Y, Huigens Iii RW.
Abouelhassan Y, et al. Among authors: huigens iii rw.
Medchemcomm. 2019 Jan 29;10(5):712-716. doi: 10.1039/c8md00613j. eCollection 2019 May 1.
Medchemcomm. 2019.
PMID: 31191861
Free PMC article.
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An ether-linked halogenated phenazine-quinone prodrug model for antibacterial applications.
Huigens Iii RW, Yang H, Liu K, Kim YS, Jin S.
Huigens Iii RW, et al.
Org Biomol Chem. 2021 Aug 5;19(30):6603-6608. doi: 10.1039/d1ob01107c.
Org Biomol Chem. 2021.
PMID: 34286808
Free PMC article.
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First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival.
Guijarro MV, Kellish PC, Dib PE, Paciaroni NG, Nawab A, Andring J, Kulemina L, Borrero NV, Modenutti C, Feely M, Nasri E, Seifert RP, Luo X, Bennett RL, Shabashvili D, Licht JD, McKenna R, Roitberg A, Huigens RW 3rd, Kaye FJ, Zajac-Kaye M.
Guijarro MV, et al.
JCI Insight. 2023 Apr 25;8(10):e158798. doi: 10.1172/jci.insight.158798.
JCI Insight. 2023.
PMID: 37097751
Free PMC article.
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