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P-selectin inhibition therapeutically promotes thrombus resolution and prevents vein wall fibrosis better than enoxaparin and an inhibitor to von Willebrand factor.
Diaz JA, Wrobleski SK, Alvarado CM, Hawley AE, Doornbos NK, Lester PA, Lowe SE, Gabriel JE, Roelofs KJ, Henke PK, Schaub RG, Wakefield TW, Myers DD Jr. Diaz JA, et al. Among authors: schaub rg. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):829-37. doi: 10.1161/ATVBAHA.114.304457. Epub 2015 Feb 5. Arterioscler Thromb Vasc Biol. 2015. PMID: 25657307 Free PMC article.
Characterization of the novel P-selectin inhibitor PSI-697 [2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] quinoline-4-carboxylic acid] in vitro and in rodent models of vascular inflammation and thrombosis.
Bedard PW, Clerin V, Sushkova N, Tchernychev B, Antrilli T, Resmini C, Keith JC Jr, Hennan JK, Kaila N, Debernardo S, Janz K, Wang Q, Crandall DL, Schaub RG, Shaw GD, Carter LL. Bedard PW, et al. Among authors: schaub rg. J Pharmacol Exp Ther. 2008 Feb;324(2):497-506. doi: 10.1124/jpet.107.128124. Epub 2007 Nov 16. J Pharmacol Exp Ther. 2008. PMID: 18024786
Novel agents that promote bone regeneration.
Schaub RG, Wozney J. Schaub RG, et al. Curr Opin Biotechnol. 1991 Dec;2(6):868-71. doi: 10.1016/s0958-1669(05)80123-5. Curr Opin Biotechnol. 1991. PMID: 1367961 Review.
126 results