Cichewicz RH - Search Results

1

Bioactivity profiling with parallel mass spectrometry reveals an assemblage of green tea metabolites affording protection against human huntingtin and alpha-synuclein toxicity.

Williams RB, Gutekunst WR, Joyner PM, Duan W, Li Q, Ross CA, Williams TD, Cichewicz RH. Williams RB, et al. Among authors: cichewicz rh. J Agric Food Chem. 2007 Nov 14;55(23):9450-6. doi: 10.1021/jf072241x. Epub 2007 Oct 19. J Agric Food Chem. 2007. PMID: 17944533

2

Probing the metabolic aberrations underlying mutant huntingtin toxicity in yeast and assessing their degree of preservation in humans and mice.

Joyner PM, Matheke RM, Smith LM, Cichewicz RH. Joyner PM, et al. Among authors: cichewicz rh. J Proteome Res. 2010 Jan;9(1):404-12. doi: 10.1021/pr900734g. J Proteome Res. 2010. PMID: 19908918 Free PMC article.

3

Bringing natural products into the fold - exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases.

Joyner PM, Cichewicz RH. Joyner PM, et al. Among authors: cichewicz rh. Nat Prod Rep. 2011 Jan;28(1):26-47. doi: 10.1039/c0np00017e. Epub 2010 Oct 7. Nat Prod Rep. 2011. PMID: 20927454 Review.

4

Briarane diterpenes diminish COX-2 expression in human colon adenocarcinoma cells.

Joyner PM, Waters AL, Williams RB, Powell DR, Janakiram NB, Rao CV, Cichewicz RH. Joyner PM, et al. Among authors: cichewicz rh. J Nat Prod. 2011 Apr 25;74(4):857-61. doi: 10.1021/np100775a. Epub 2011 Mar 25. J Nat Prod. 2011. PMID: 21438584

5

A chemical epigenetics approach for engineering the in situ biosynthesis of a cryptic natural product from Aspergillus niger.

Henrikson JC, Hoover AR, Joyner PM, Cichewicz RH. Henrikson JC, et al. Among authors: cichewicz rh. Org Biomol Chem. 2009 Feb 7;7(3):435-8. doi: 10.1039/b819208a. Epub 2008 Dec 11. Org Biomol Chem. 2009. PMID: 19156306

6

Mutanobactin A from the human oral pathogen Streptococcus mutans is a cross-kingdom regulator of the yeast-mycelium transition.

Joyner PM, Liu J, Zhang Z, Merritt J, Qi F, Cichewicz RH. Joyner PM, et al. Among authors: cichewicz rh. Org Biomol Chem. 2010 Dec 21;8(24):5486-9. doi: 10.1039/c0ob00579g. Epub 2010 Sep 20. Org Biomol Chem. 2010. PMID: 20852771 Free PMC article.

7

Epigenetic remodeling of the fungal secondary metabolome.

Williams RB, Henrikson JC, Hoover AR, Lee AE, Cichewicz RH. Williams RB, et al. Among authors: cichewicz rh. Org Biomol Chem. 2008 Jun 7;6(11):1895-7. doi: 10.1039/b804701d. Epub 2008 Apr 14. Org Biomol Chem. 2008. PMID: 18480899

8

trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease.

Fu J, Jin J, Cichewicz RH, Hageman SA, Ellis TK, Xiang L, Peng Q, Jiang M, Arbez N, Hotaling K, Ross CA, Duan W. Fu J, et al. Among authors: cichewicz rh. J Biol Chem. 2012 Jul 13;287(29):24460-72. doi: 10.1074/jbc.M112.382226. Epub 2012 May 30. J Biol Chem. 2012. PMID: 22648412 Free PMC article.

9

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.

Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W. Jiang M, et al. Among authors: cichewicz rh. Nat Med. 2011 Dec 18;18(1):153-8. doi: 10.1038/nm.2558. Nat Med. 2011. PMID: 22179319 Free PMC article.

10

Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum.

Wang X, Sena Filho JG, Hoover AR, King JB, Ellis TK, Powell DR, Cichewicz RH. Wang X, et al. Among authors: cichewicz rh. J Nat Prod. 2010 May 28;73(5):942-8. doi: 10.1021/np100142h. J Nat Prod. 2010. PMID: 20450206 Free PMC article.

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