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A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.
Steidl U, Steidl C, Ebralidze A, Chapuy B, Han HJ, Will B, Rosenbauer F, Becker A, Wagner K, Koschmieder S, Kobayashi S, Costa DB, Schulz T, O'Brien KB, Verhaak RG, Delwel R, Haase D, Trümper L, Krauter J, Kohwi-Shigematsu T, Griesinger F, Tenen DG. Steidl U, et al. Among authors: steidl c. J Clin Invest. 2007 Sep;117(9):2611-20. doi: 10.1172/JCI30525. J Clin Invest. 2007. PMID: 17694175 Free PMC article.
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Ebralidze AK, Guibal FC, Steidl U, Zhang P, Lee S, Bartholdy B, Jorda MA, Petkova V, Rosenbauer F, Huang G, Dayaram T, Klupp J, O'Brien KB, Will B, Hoogenkamp M, Borden KL, Bonifer C, Tenen DG. Ebralidze AK, et al. Among authors: steidl u. Genes Dev. 2008 Aug 1;22(15):2085-92. doi: 10.1101/gad.1654808. Genes Dev. 2008. PMID: 18676813 Free PMC article.
174 results