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Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Bioorg Med Chem Lett. 2004 Jul 16;14(14):3639-43. doi: 10.1016/j.bmcl.2004.05.025.
Bioorg Med Chem Lett. 2004.
PMID: 15203134
Novel compounds designed as antistress agents.
Tsiakitzis KC, Rekka EA, Kourounakis AP, Kourounakis PN.
Tsiakitzis KC, et al.
J Med Chem. 2009 Nov 26;52(22):7315-8. doi: 10.1021/jm901169b.
J Med Chem. 2009.
PMID: 19863055
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Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties.
Doulgkeris CM, Galanakis D, Kourounakis AP, Tsiakitzis KC, Gavalas AM, Eleftheriou PT, Victoratos P, Rekka EA, Kourounakis PN.
Doulgkeris CM, et al. Among authors: tsiakitzis kc.
Bioorg Med Chem Lett. 2006 Feb 15;16(4):825-9. doi: 10.1016/j.bmcl.2005.11.027. Epub 2005 Nov 23.
Bioorg Med Chem Lett. 2006.
PMID: 16309906
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Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile.
Ziakas GN, Rekka EA, Gavalas AM, Eleftheriou PT, Tsiakitzis KC, Kourounakis PN.
Ziakas GN, et al. Among authors: tsiakitzis kc.
Bioorg Med Chem. 2005 Dec 1;13(23):6485-92. doi: 10.1016/j.bmc.2005.07.049. Epub 2005 Sep 26.
Bioorg Med Chem. 2005.
PMID: 16185877
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