Mistry P - Search Results

1

Structure-activity relationships for analogues of the phenazine-based dual topoisomerase I/II inhibitor XR11576.

Wang S, Miller W, Milton J, Vicker N, Stewart A, Charlton P, Mistry P, Hardick D, Denny WA. Wang S, et al. Among authors: mistry p. Bioorg Med Chem Lett. 2002 Feb 11;12(3):415-8. doi: 10.1016/s0960-894x(01)00770-3. Bioorg Med Chem Lett. 2002. PMID: 11814810

2

Novel angular benzophenazines: dual topoisomerase I and topoisomerase II inhibitors as potential anticancer agents.

Vicker N, Burgess L, Chuckowree IS, Dodd R, Folkes AJ, Hardick DJ, Hancox TC, Miller W, Milton J, Sohal S, Wang S, Wren SP, Charlton PA, Dangerfield W, Liddle C, Mistry P, Stewart AJ, Denny WA. Vicker N, et al. Among authors: mistry p. J Med Chem. 2002 Jan 31;45(3):721-39. doi: 10.1021/jm010329a. J Med Chem. 2002. PMID: 11806724

3

Structure-activity relationships for pyrido-, imidazo-, pyrazolo-, pyrazino-, and pyrrolophenazinecarboxamides as topoisomerase-targeted anticancer agents.

Gamage SA, Spicer JA, Rewcastle GW, Milton J, Sohal S, Dangerfield W, Mistry P, Vicker N, Charlton PA, Denny WA. Gamage SA, et al. Among authors: mistry p. J Med Chem. 2002 Jan 31;45(3):740-3. doi: 10.1021/jm010330+. J Med Chem. 2002. PMID: 11806725

4

In vitro and in vivo characterization of XR11576, a novel, orally active, dual inhibitor of topoisomerase I and II.

Mistry P, Stewart AJ, Dangerfield W, Baker M, Liddle C, Bootle D, Kofler B, Laurie D, Denny WA, Baguley B, Charlton PA. Mistry P, et al. Anticancer Drugs. 2002 Jan;13(1):15-28. doi: 10.1097/00001813-200201000-00002. Anticancer Drugs. 2002. PMID: 11914637

5

Studies on pyrrolopyrimidines as selective inhibitors of multidrug-resistance-associated protein in multidrug resistance.

Wang S, Folkes A, Chuckowree I, Cockcroft X, Sohal S, Miller W, Milton J, Wren SP, Vicker N, Depledge P, Scott J, Smith L, Jones H, Mistry P, Faint R, Thompson D, Cocks S. Wang S, et al. Among authors: mistry p. J Med Chem. 2004 Mar 11;47(6):1329-38. doi: 10.1021/jm031011g. J Med Chem. 2004. PMID: 14998323

6

Design and synthesis of new templates derived from pyrrolopyrimidine as selective multidrug-resistance-associated protein inhibitors in multidrug resistance.

Wang S, Wan NC, Harrison J, Miller W, Chuckowree I, Sohal S, Hancox TC, Baker S, Folkes A, Wilson F, Thompson D, Cocks S, Farmer H, Boyce A, Freathy C, Broadbridge J, Scott J, Depledge P, Faint R, Mistry P, Charlton P. Wang S, et al. Among authors: mistry p. J Med Chem. 2004 Mar 11;47(6):1339-50. doi: 10.1021/jm0310129. J Med Chem. 2004. PMID: 14998324

7

Mode of action of the novel phenazine anticancer agents XR11576 and XR5944.

Lewis LJ, Mistry P, Charlton PA, Thomas H, Coley HM. Lewis LJ, et al. Among authors: mistry p. Anticancer Drugs. 2007 Feb;18(2):139-48. doi: 10.1097/CAD.0b013e328010772f. Anticancer Drugs. 2007. PMID: 17159600

8

Antitumor activity of XR5944, a novel and potent topoisomerase poison.

Stewart AJ, Mistry P, Dangerfield W, Bootle D, Baker M, Kofler B, Okiji S, Baguley BC, Denny WA, Charlton PA. Stewart AJ, et al. Among authors: mistry p. Anticancer Drugs. 2001 Apr;12(4):359-67. doi: 10.1097/00001813-200104000-00009. Anticancer Drugs. 2001. PMID: 11335793

9

Preclinical anti-tumor activity of XR5944 in combination with carboplatin or doxorubicin in non-small-cell lung carcinoma.

Harris SM, Scott JA, Brown JL, Charlton PA, Mistry P. Harris SM, et al. Among authors: mistry p. Anticancer Drugs. 2005 Oct;16(9):945-51. doi: 10.1097/01.cad.0000176499.17939.56. Anticancer Drugs. 2005. PMID: 16162971

10

Effect of phenazine compounds XR11576 and XR5944 on DNA topoisomerases.

Jobson AG, Willmore E, Tilby MJ, Mistry P, Charlton P, Austin CA. Jobson AG, et al. Among authors: mistry p. Cancer Chemother Pharmacol. 2009 Apr;63(5):889-901. doi: 10.1007/s00280-008-0812-9. Epub 2008 Aug 5. Cancer Chemother Pharmacol. 2009. PMID: 18679685

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