Trail PA - Search Results

1

Synthesis of an immunoconjugate of camptothecin.

Walker MA, Dubowchik GM, Hofstead SJ, Trail PA, Firestone RA. Walker MA, et al. Among authors: trail pa. Bioorg Med Chem Lett. 2002 Jan 21;12(2):217-9. doi: 10.1016/s0960-894x(01)00707-7. Bioorg Med Chem Lett. 2002. PMID: 11755358

2

Monoclonal antibody mediated intracellular targeting of tallysomycin S(10b).

Walker MA, King HD, Dalterio RA, Trail P, Firestone R, Dubowchik GM. Walker MA, et al. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4323-7. doi: 10.1016/j.bmcl.2004.05.089. Bioorg Med Chem Lett. 2004. PMID: 15261295

3

Doxorubicin immunoconjugates containing bivalent, lysosomally-cleavable dipeptide linkages.

Dubowchik GM, Radia S, Mastalerz H, Walker MA, Firestone RA, Dalton King H, Hofstead SJ, Willner D, Lasch SJ, Trail PA. Dubowchik GM, et al. Among authors: trail pa. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1529-32. doi: 10.1016/s0960-894x(02)00194-4. Bioorg Med Chem Lett. 2002. PMID: 12031335

4

Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity.

Dubowchik GM, Firestone RA, Padilla L, Willner D, Hofstead SJ, Mosure K, Knipe JO, Lasch SJ, Trail PA. Dubowchik GM, et al. Among authors: trail pa. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69. doi: 10.1021/bc025536j. Bioconjug Chem. 2002. PMID: 12121142

5

Monoclonal antibody conjugates of doxorubicin prepared with branched peptide linkers: inhibition of aggregation by methoxytriethyleneglycol chains.

King HD, Dubowchik GM, Mastalerz H, Willner D, Hofstead SJ, Firestone RA, Lasch SJ, Trail PA. King HD, et al. Among authors: trail pa. J Med Chem. 2002 Sep 12;45(19):4336-43. doi: 10.1021/jm020149g. J Med Chem. 2002. PMID: 12213074

6

BR96 conjugates of highly potent anthracyclines.

King HD, Staab AJ, Pham-Kaplita K, Yurgaitis D, Firestone RA, Lasch SJ, Trail PA. King HD, et al. Among authors: trail pa. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2119-22. doi: 10.1016/s0960-894x(03)00375-5. Bioorg Med Chem Lett. 2003. PMID: 12798317

7

(6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin.

Willner D, Trail PA, Hofstead SJ, King HD, Lasch SJ, Braslawsky GR, Greenfield RS, Kaneko T, Firestone RA. Willner D, et al. Among authors: trail pa. Bioconjug Chem. 1993 Nov-Dec;4(6):521-7. doi: 10.1021/bc00024a015. Bioconjug Chem. 1993. PMID: 7508268

8

Effect of linker variation on the stability, potency, and efficacy of carcinoma-reactive BR64-doxorubicin immunoconjugates.

Trail PA, Willner D, Knipe J, Henderson AJ, Lasch SJ, Zoeckler ME, TrailSmith MD, Doyle TW, King HD, Casazza AM, Braslawsky GR, Brown J, Hofstead SJ, Greenfield RS, Firestone RA, Mosure K, Kadow KF, Yang MB, Hellström KE, Hellström I. Trail PA, et al. Cancer Res. 1997 Jan 1;57(1):100-5. Cancer Res. 1997. PMID: 8988048

9

Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates.

King HD, Yurgaitis D, Willner D, Firestone RA, Yang MB, Lasch SJ, Hellström KE, Trail PA. King HD, et al. Among authors: trail pa. Bioconjug Chem. 1999 Mar-Apr;10(2):279-88. doi: 10.1021/bc980100i. Bioconjug Chem. 1999. PMID: 10077478

10

Antibody drug conjugates for treatment of breast cancer: Novel targets and diverse approaches in ADC design.

Trail PA, Dubowchik GM, Lowinger TB. Trail PA, et al. Pharmacol Ther. 2018 Jan;181:126-142. doi: 10.1016/j.pharmthera.2017.07.013. Epub 2017 Jul 27. Pharmacol Ther. 2018. PMID: 28757155 Review.

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