Dubowchik GM - Search Results

1

Synthesis of an immunoconjugate of camptothecin.

Walker MA, Dubowchik GM, Hofstead SJ, Trail PA, Firestone RA. Walker MA, et al. Among authors: dubowchik gm. Bioorg Med Chem Lett. 2002 Jan 21;12(2):217-9. doi: 10.1016/s0960-894x(01)00707-7. Bioorg Med Chem Lett. 2002. PMID: 11755358

2

Improved cytotoxicity of antitumor compounds deliverable by the LDL pathway.

Dubowchik GM, Firestone RA. Dubowchik GM, et al. Bioconjug Chem. 1995 Jul-Aug;6(4):427-39. doi: 10.1021/bc00034a013. Bioconjug Chem. 1995. PMID: 7578363

3

Reversal of doxorubicin resistance and catalytic neutralization of lysosomes by a lipophilic imidazole.

Dubowchik GM, Padilla L, Edinger K, Firestone RA. Dubowchik GM, et al. Biochim Biophys Acta. 1994 Apr 20;1191(1):103-8. doi: 10.1016/0005-2736(94)90237-2. Biochim Biophys Acta. 1994. PMID: 8155664

4

Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin.

Dubowchik GM, Firestone RA. Dubowchik GM, et al. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3341-6. doi: 10.1016/s0960-894x(98)00609-x. Bioorg Med Chem Lett. 1998. PMID: 9873731

5

Cathepsin B-sensitive dipeptide prodrugs. 2. Models of anticancer drugs paclitaxel (Taxol), mitomycin C and doxorubicin.

Dubowchik GM, Mosure K, Knipe JO, Firestone RA. Dubowchik GM, et al. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3347-52. doi: 10.1016/s0960-894x(98)00610-6. Bioorg Med Chem Lett. 1998. PMID: 9873732

6

Receptor-mediated and enzyme-dependent targeting of cytotoxic anticancer drugs.

Dubowchik GM, Walker MA. Dubowchik GM, et al. Pharmacol Ther. 1999 Aug;83(2):67-123. doi: 10.1016/s0163-7258(99)00018-2. Pharmacol Ther. 1999. PMID: 10511457 Review.

7

Induction of cell death by the lysosomotropic detergent MSDH.

Li W, Yuan X, Nordgren G, Dalen H, Dubowchik GM, Firestone RA, Brunk UT. Li W, et al. Among authors: dubowchik gm. FEBS Lett. 2000 Mar 17;470(1):35-9. doi: 10.1016/s0014-5793(00)01286-2. FEBS Lett. 2000. PMID: 10722841 Free article.

8

Fluoresceinated FKBP12 ligands for a high-throughput fluorescence polarization assay.

Dubowchik GM, Ditta JL, Herbst JJ, Bollini S, Vinitsky A. Dubowchik GM, et al. Bioorg Med Chem Lett. 2000 Mar 20;10(6):559-62. doi: 10.1016/s0960-894x(00)00045-7. Bioorg Med Chem Lett. 2000. PMID: 10741553

9

Amines That Transport Protons across Bilayer Membranes: Synthesis, Lysosomal Neutralization, and Two-Phase pK(a) Values by NMR.

Dubowchik GM, Padilla L, Edinger K, Firestone RA. Dubowchik GM, et al. J Org Chem. 1996 Jul 12;61(14):4676-4684. doi: 10.1021/jo960367f. J Org Chem. 1996. PMID: 11667396

10

Doxorubicin immunoconjugates containing bivalent, lysosomally-cleavable dipeptide linkages.

Dubowchik GM, Radia S, Mastalerz H, Walker MA, Firestone RA, Dalton King H, Hofstead SJ, Willner D, Lasch SJ, Trail PA. Dubowchik GM, et al. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1529-32. doi: 10.1016/s0960-894x(02)00194-4. Bioorg Med Chem Lett. 2002. PMID: 12031335

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