Background: Random-effects meta-analysis within a hierarchical normal modeling framework is commonly implemented in a wide range of evidence synthesis applications. More general problems may even be tackled when considering meta-regression approaches that in addition allow for the inclusion of study-level covariables.
Methods: We describe the Bayesian meta-regression implementation provided in the bayesmetaR package including the choice of priors, and we illustrate its practical use.
Results: A wide range of example applications are given, such as binary and continuous covariables, subgroup analysis, indirect comparisons, and model selection. Example R code is provided.
Conclusions: The bayesmeta package provides a flexible implementation. Due to the avoidance of MCMC methods, computations are fast and reproducible, facilitating quick sensitivity checks or large-scale simulation studies.
Keywords: Covariables; Heterogeneity; Meta-analysis; Moderators; Subgroup analysis.
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