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Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation.
Müller F, Lim JKM, Bebber CM, Seidel E, Tishina S, Dahlhaus A, Stroh J, Beck J, Yapici FI, Nakayama K, Torres Fernández L, Brägelmann J, Leprivier G, von Karstedt S. Müller F, et al. Among authors: von karstedt s. Cell Death Differ. 2023 Feb;30(2):442-456. doi: 10.1038/s41418-022-01096-8. Epub 2022 Nov 29. Cell Death Differ. 2023. PMID: 36443441 Free PMC article.
Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
Lim JKM, Delaidelli A, Minaker SW, Zhang HF, Colovic M, Yang H, Negri GL, von Karstedt S, Lockwood WW, Schaffer P, Leprivier G, Sorensen PH. Lim JKM, et al. Among authors: von karstedt s. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9433-9442. doi: 10.1073/pnas.1821323116. Epub 2019 Apr 18. Proc Natl Acad Sci U S A. 2019. PMID: 31000598 Free PMC article.
Ferroptosis in Cancer Cell Biology.
Bebber CM, Müller F, Prieto Clemente L, Weber J, von Karstedt S. Bebber CM, et al. Among authors: von karstedt s. Cancers (Basel). 2020 Jan 9;12(1):164. doi: 10.3390/cancers12010164. Cancers (Basel). 2020. PMID: 31936571 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 33563927
Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes.
Bebber CM, Thomas ES, Stroh J, Chen Z, Androulidaki A, Schmitt A, Höhne MN, Stüker L, de Pádua Alves C, Khonsari A, Dammert MA, Parmaksiz F, Tumbrink HL, Beleggia F, Sos ML, Riemer J, George J, Brodesser S, Thomas RK, Reinhardt HC, von Karstedt S. Bebber CM, et al. Among authors: von karstedt s. Nat Commun. 2021 Apr 6;12(1):2048. doi: 10.1038/s41467-021-22336-4. Nat Commun. 2021. PMID: 33824345 Free PMC article.
TRAIL-receptor 2-a novel negative regulator of p53.
Willms A, Schupp H, Poelker M, Adawy A, Debus JF, Hartwig T, Krichel T, Fritsch J, Singh S, Walczak H, von Karstedt S, Schäfer H, Trauzold A. Willms A, et al. Among authors: von karstedt s. Cell Death Dis. 2021 Jul 31;12(8):757. doi: 10.1038/s41419-021-04048-1. Cell Death Dis. 2021. PMID: 34333527 Free PMC article.
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann J, Lorenz C, Borchmann S, Nishii K, Wegner J, Meder L, Ostendorp J, Ast DF, Heimsoeth A, Nakasuka T, Hirabae A, Okawa S, Dammert MA, Plenker D, Klein S, Lohneis P, Gu J, Godfrey LK, Forster J, Trajkovic-Arsic M, Zillinger T, Haarmann M, Quaas A, Lennartz S, Schmiel M, D'Rozario J, Thomas ES, Li H, Schmitt CA, George J, Thomas RK, von Karstedt S, Hartmann G, Büttner R, Ullrich RT, Siveke JT, Ohashi K, Schlee M, Sos ML. Brägelmann J, et al. Among authors: von karstedt s. Nat Commun. 2021 Sep 17;12(1):5505. doi: 10.1038/s41467-021-25728-8. Nat Commun. 2021. PMID: 34535668 Free PMC article.
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