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Sex- and age-dependent genetics of longevity in a heterogeneous mouse population.
Bou Sleiman M, Roy S, Gao AW, Sadler MC, von Alvensleben GVG, Li H, Sen S, Harrison DE, Nelson JF, Strong R, Miller RA, Kutalik Z, Williams RW, Auwerx J. Bou Sleiman M, et al. Among authors: von alvensleben gvg. Science. 2022 Sep 30;377(6614):eabo3191. doi: 10.1126/science.abo3191. Epub 2022 Sep 30. Science. 2022. PMID: 36173858 Free PMC article.
Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis.
Li H, Perino A, Huang Q, Von Alvensleben GVG, Banaei-Esfahani A, Velazquez-Villegas LA, Gariani K, Korbelius M, Bou Sleiman M, Imbach J, Sun Y, Li X, Bachmann A, Goeminne LJE, Gallart-Ayala H, Williams EG, Ivanisevic J, Auwerx J, Schoonjans K. Li H, et al. Among authors: von alvensleben gvg. Cell Metab. 2022 Oct 4;34(10):1594-1610.e4. doi: 10.1016/j.cmet.2022.08.015. Epub 2022 Sep 12. Cell Metab. 2022. PMID: 36099916 Free PMC article.
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression.
Benegiamo G, von Alvensleben GVG, Rodríguez-López S, Goeminne LJE, Bachmann AM, Morel JD, Broeckx E, Ma JY, Carreira V, Youssef SA, Azhar N, Reilly DF, D'Aquino K, Mullican S, Bou-Sleiman M, Auwerx J. Benegiamo G, et al. Among authors: von alvensleben gvg. J Exp Med. 2023 Apr 3;220(4):e20221738. doi: 10.1084/jem.20221738. Epub 2023 Feb 14. J Exp Med. 2023. PMID: 36787127 Free PMC article.