van der Ven LTM - Search Results

1

Fish embryo toxicity test, threshold approach, and moribund as approaches to implement 3R principles to the acute fish toxicity test.

Dang Z, van der Ven LTM, Kienhuis AS. Dang Z, et al. Among authors: van der ven ltm. Chemosphere. 2017 Nov;186:677-685. doi: 10.1016/j.chemosphere.2017.08.047. Epub 2017 Aug 11. Chemosphere. 2017. PMID: 28818595 Review.

2

Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.

Kienhuis AS, Bessems JG, Pennings JL, Driessen M, Luijten M, van Delft JH, Peijnenburg AA, van der Ven LT. Kienhuis AS, et al. Toxicol Appl Pharmacol. 2011 Jan 15;250(2):96-107. doi: 10.1016/j.taap.2010.10.013. Epub 2010 Oct 21. Toxicol Appl Pharmacol. 2011. PMID: 20970440 Review.

3

Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling.

Driessen M, Kienhuis AS, Pennings JL, Pronk TE, van de Brandhof EJ, Roodbergen M, Spaink HP, van de Water B, van der Ven LT. Driessen M, et al. Arch Toxicol. 2013 May;87(5):807-23. doi: 10.1007/s00204-013-1039-z. Epub 2013 Apr 6. Arch Toxicol. 2013. PMID: 23559145

4

Mechanisms of amiodarone and valproic acid induced liver steatosis in mouse in vivo act as a template for other hepatotoxicity models.

Vitins AP, Kienhuis AS, Speksnijder EN, Roodbergen M, Luijten M, van der Ven LT. Vitins AP, et al. Arch Toxicol. 2014 Aug;88(8):1573-88. doi: 10.1007/s00204-014-1211-0. Epub 2014 Feb 18. Arch Toxicol. 2014. PMID: 24535564

5

Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans.

Driessen M, Kienhuis AS, Vitins AP, Pennings JL, Pronk TE, van den Brandhof EJ, Roodbergen M, van de Water B, van der Ven LT. Driessen M, et al. Toxicol Lett. 2014 Oct 1;230(1):48-56. doi: 10.1016/j.toxlet.2014.06.844. Epub 2014 Jul 24. Toxicol Lett. 2014. PMID: 25064622

6

A transcriptomics-based hepatotoxicity comparison between the zebrafish embryo and established human and rodent in vitro and in vivo models using cyclosporine A, amiodarone and acetaminophen.

Driessen M, Vitins AP, Pennings JL, Kienhuis AS, Water Bv, van der Ven LT. Driessen M, et al. Toxicol Lett. 2015 Jan 22;232(2):403-12. doi: 10.1016/j.toxlet.2014.11.020. Epub 2014 Nov 24. Toxicol Lett. 2015. PMID: 25448281

7

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis.

Kienhuis AS, Vitins AP, Pennings JL, Pronk TE, Speksnijder EN, Roodbergen M, van Delft JH, Luijten M, van der Ven LT. Kienhuis AS, et al. Toxicol Lett. 2013 Aug 29;221(3):225-36. doi: 10.1016/j.toxlet.2013.06.236. Epub 2013 Jul 3. Toxicol Lett. 2013. PMID: 23830897

8

Identification of proteome markers for drug-induced liver injury in zebrafish embryos.

Driessen M, van der Plas-Duivesteijn S, Kienhuis AS, van den Brandhof EJ, Roodbergen M, van de Water B, Spaink HP, Palmblad M, van der Ven LTM, Pennings JLA. Driessen M, et al. Among authors: van der ven ltm. Toxicology. 2022 Jul;477:153262. doi: 10.1016/j.tox.2022.153262. Epub 2022 Jul 20. Toxicology. 2022. PMID: 35868597

9

OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing.

Busquet F, Strecker R, Rawlings JM, Belanger SE, Braunbeck T, Carr GJ, Cenijn P, Fochtman P, Gourmelon A, Hübler N, Kleensang A, Knöbel M, Kussatz C, Legler J, Lillicrap A, Martínez-Jerónimo F, Polleichtner C, Rzodeczko H, Salinas E, Schneider KE, Scholz S, van den Brandhof EJ, van der Ven LT, Walter-Rohde S, Weigt S, Witters H, Halder M. Busquet F, et al. Regul Toxicol Pharmacol. 2014 Aug;69(3):496-511. doi: 10.1016/j.yrtph.2014.05.018. Epub 2014 May 27. Regul Toxicol Pharmacol. 2014. PMID: 24874798 Free article.

10

The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish.

van der Ven LTM, Schoonen WG, Groot RM, den Ouden F, Heusinkveld HJ, Zwart EP, Hodemaekers HM, Rorije E, de Knecht J. van der Ven LTM, et al. Toxicol Appl Pharmacol. 2020 Nov 15;407:115249. doi: 10.1016/j.taap.2020.115249. Epub 2020 Sep 24. Toxicol Appl Pharmacol. 2020. PMID: 32979392

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