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Transcriptional bursts and heterogeneity among cardiomyocytes in hypertrophic cardiomyopathy.
Burkart V, Kowalski K, Aldag-Niebling D, Beck J, Frick DA, Holler T, Radocaj A, Piep B, Zeug A, Hilfiker-Kleiner D, Dos Remedios CG, van der Velden J, Montag J, Kraft T. Burkart V, et al. Among authors: van der velden j. Front Cardiovasc Med. 2022 Aug 23;9:987889. doi: 10.3389/fcvm.2022.987889. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36082122 Free PMC article.
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
Wijnker PJ, Foster DB, Tsao AL, Frazier AH, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: van der velden j. Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H260-8. doi: 10.1152/ajpheart.00498.2012. Epub 2012 Nov 9. Am J Physiol Heart Circ Physiol. 2013. PMID: 23144315 Free PMC article.
GSK3β phosphorylates newly identified site in the proline-alanine-rich region of cardiac myosin-binding protein C and alters cross-bridge cycling kinetics in human: short communication.
Kuster DW, Sequeira V, Najafi A, Boontje NM, Wijnker PJ, Witjas-Paalberends ER, Marston SB, Dos Remedios CG, Carrier L, Demmers JA, Redwood C, Sadayappan S, van der Velden J. Kuster DW, et al. Among authors: van der velden j. Circ Res. 2013 Feb 15;112(4):633-9. doi: 10.1161/CIRCRESAHA.112.275602. Epub 2012 Dec 31. Circ Res. 2013. PMID: 23277198 Free PMC article.
Familial hypertrophic cardiomyopathy: functional effects of myosin mutation R723G in cardiomyocytes.
Kraft T, Witjas-Paalberends ER, Boontje NM, Tripathi S, Brandis A, Montag J, Hodgkinson JL, Francino A, Navarro-Lopez F, Brenner B, Stienen GJ, van der Velden J. Kraft T, et al. Among authors: van der velden j. J Mol Cell Cardiol. 2013 Apr;57:13-22. doi: 10.1016/j.yjmcc.2013.01.001. Epub 2013 Jan 11. J Mol Cell Cardiol. 2013. PMID: 23318932 Free article.
Titin gene mutations are common in families with both peripartum cardiomyopathy and dilated cardiomyopathy.
van Spaendonck-Zwarts KY, Posafalvi A, van den Berg MP, Hilfiker-Kleiner D, Bollen IA, Sliwa K, Alders M, Almomani R, van Langen IM, van der Meer P, Sinke RJ, van der Velden J, Van Veldhuisen DJ, van Tintelen JP, Jongbloed JD. van Spaendonck-Zwarts KY, et al. Among authors: van den berg mp, van der meer p, van langen im, van der velden j, van tintelen jp, van veldhuisen dj. Eur Heart J. 2014 Aug 21;35(32):2165-73. doi: 10.1093/eurheartj/ehu050. Epub 2014 Feb 20. Eur Heart J. 2014. PMID: 24558114
Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation.
Wijnker PJ, Sequeira V, Foster DB, Li Y, Dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: van der velden j. Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1171-81. doi: 10.1152/ajpheart.00580.2013. Epub 2014 Feb 28. Am J Physiol Heart Circ Physiol. 2014. PMID: 24585778 Free PMC article.
Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2+)-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes.
Wijnker PJ, Sequeira V, Witjas-Paalberends ER, Foster DB, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: van der velden j. Arch Biochem Biophys. 2014 Jul 15;554:11-21. doi: 10.1016/j.abb.2014.04.017. Epub 2014 May 9. Arch Biochem Biophys. 2014. PMID: 24814372 Free PMC article.
Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation.
Witjas-Paalberends ER, Ferrara C, Scellini B, Piroddi N, Montag J, Tesi C, Stienen GJ, Michels M, Ho CY, Kraft T, Poggesi C, van der Velden J. Witjas-Paalberends ER, et al. Among authors: van der velden j. J Physiol. 2014 Aug 1;592(15):3257-72. doi: 10.1113/jphysiol.2014.274571. Epub 2014 Jun 13. J Physiol. 2014. PMID: 24928957 Free PMC article.
Contractile dysfunction of left ventricular cardiomyocytes in patients with pulmonary arterial hypertension.
Manders E, Bogaard HJ, Handoko ML, van de Veerdonk MC, Keogh A, Westerhof N, Stienen GJ, Dos Remedios CG, Humbert M, Dorfmüller P, Fadel E, Guignabert C, van der Velden J, Vonk-Noordegraaf A, de Man FS, Ottenheijm CA. Manders E, et al. Among authors: van de veerdonk mc, van der velden j. J Am Coll Cardiol. 2014 Jul 8;64(1):28-37. doi: 10.1016/j.jacc.2014.04.031. J Am Coll Cardiol. 2014. PMID: 24998125 Free article.
609 results