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Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.
van der Noord VE, van der Stel W, Louwerens G, Verhoeven D, Kuiken HJ, Lieftink C, Grandits M, Ecker GF, Beijersbergen RL, Bouwman P, Le Dévédec SE, van de Water B. van der Noord VE, et al. Among authors: van der stel w. Breast Cancer Res. 2023 May 5;25(1):51. doi: 10.1186/s13058-023-01648-x. Breast Cancer Res. 2023. PMID: 37147730 Free PMC article.
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation.
van der Stel W, Yang H, Vrijenhoek NG, Schimming JP, Callegaro G, Carta G, Darici S, Delp J, Forsby A, White A, le Dévédec S, Leist M, Jennings P, Beltman JB, van de Water B, Danen EHJ. van der Stel W, et al. Arch Toxicol. 2022 Jan;96(1):259-285. doi: 10.1007/s00204-021-03160-7. Epub 2021 Oct 13. Arch Toxicol. 2022. PMID: 34642769 Free PMC article.
Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors.
Delp J, Cediel-Ulloa A, Suciu I, Kranaster P, van Vugt-Lussenburg BM, Munic Kos V, van der Stel W, Carta G, Bennekou SH, Jennings P, van de Water B, Forsby A, Leist M. Delp J, et al. Among authors: van der stel w, van de water b, van vugt lussenburg bm. Arch Toxicol. 2021 Feb;95(2):591-615. doi: 10.1007/s00204-020-02970-5. Epub 2021 Jan 29. Arch Toxicol. 2021. PMID: 33512557 Free PMC article.
New approach methods (NAMs) supporting read-across: Two neurotoxicity AOP-based IATA case studies.
Van der Stel W, Carta G, Eakins J, Delp J, Suciu I, Forsby A, Cediel-Ulloa A, Attoff K, Troger F, Kamp H, Gardner I, Zdrazil B, Moné MJ, Ecker GF, Pastor M, Gómez-Tamayo JC, White A, Danen EHJ, Leist M, Walker P, Jennings P, Hougaard Bennekou S, Van de Water B. Van der Stel W, et al. ALTEX. 2021;38(4):615-635. doi: 10.14573/altex.2103051. Epub 2021 Jun 10. ALTEX. 2021. PMID: 34114044 Free article.
Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.
van der Stel W, Carta G, Eakins J, Darici S, Delp J, Forsby A, Bennekou SH, Gardner I, Leist M, Danen EHJ, Walker P, van de Water B, Jennings P. van der Stel W, et al. Among authors: van de water b. Arch Toxicol. 2020 Aug;94(8):2707-2729. doi: 10.1007/s00204-020-02792-5. Epub 2020 Jul 18. Arch Toxicol. 2020. PMID: 32607615 Free PMC article.
15 results