Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

329 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array.
Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Zetsche B, et al. Among authors: van der oost j. Nat Biotechnol. 2017 Jan;35(1):31-34. doi: 10.1038/nbt.3737. Epub 2016 Dec 5. Nat Biotechnol. 2017. PMID: 27918548 Free PMC article.
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3.
Westra ER, van Erp PB, Künne T, Wong SP, Staals RH, Seegers CL, Bollen S, Jore MM, Semenova E, Severinov K, de Vos WM, Dame RT, de Vries R, Brouns SJ, van der Oost J. Westra ER, et al. Among authors: van der oost j, van erp pb. Mol Cell. 2012 Jun 8;46(5):595-605. doi: 10.1016/j.molcel.2012.03.018. Epub 2012 Apr 19. Mol Cell. 2012. PMID: 22521689 Free PMC article.
Effects of Argonaute on Gene Expression in Thermus thermophilus.
Swarts DC, Koehorst JJ, Westra ER, Schaap PJ, van der Oost J. Swarts DC, et al. Among authors: van der oost j. PLoS One. 2015 Apr 22;10(4):e0124880. doi: 10.1371/journal.pone.0124880. eCollection 2015. PLoS One. 2015. PMID: 25902012 Free PMC article.
An updated evolutionary classification of CRISPR-Cas systems.
Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, Saunders SJ, Barrangou R, Brouns SJ, Charpentier E, Haft DH, Horvath P, Moineau S, Mojica FJ, Terns RM, Terns MP, White MF, Yakunin AF, Garrett RA, van der Oost J, Backofen R, Koonin EV. Makarova KS, et al. Among authors: van der oost j. Nat Rev Microbiol. 2015 Nov;13(11):722-36. doi: 10.1038/nrmicro3569. Epub 2015 Sep 28. Nat Rev Microbiol. 2015. PMID: 26411297 Free PMC article. Review.
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F. Zetsche B, et al. Among authors: van der oost j. Cell. 2015 Oct 22;163(3):759-71. doi: 10.1016/j.cell.2015.09.038. Epub 2015 Sep 25. Cell. 2015. PMID: 26422227 Free PMC article.
Next Generation Prokaryotic Engineering: The CRISPR-Cas Toolkit.
Mougiakos I, Bosma EF, de Vos WM, van Kranenburg R, van der Oost J. Mougiakos I, et al. Among authors: van kranenburg r, van der oost j. Trends Biotechnol. 2016 Jul;34(7):575-587. doi: 10.1016/j.tibtech.2016.02.004. Epub 2016 Mar 2. Trends Biotechnol. 2016. PMID: 26944793 Review.
329 results