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The glycoprotein VI-phospholipase Cgamma2 signaling pathway controls thrombus formation induced by collagen and tissue factor in vitro and in vivo.
Munnix IC, Strehl A, Kuijpers MJ, Auger JM, van der Meijden PE, van Zandvoort MA, oude Egbrink MG, Nieswandt B, Heemskerk JW. Munnix IC, et al. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2673-8. doi: 10.1161/01.ATV.0000193568.71980.4a. Epub 2005 Oct 27. Arterioscler Thromb Vasc Biol. 2005. PMID: 16254207
Dual P2Y 12 receptor signaling in thrombin-stimulated platelets--involvement of phosphoinositide 3-kinase beta but not gamma isoform in Ca2+ mobilization and procoagulant activity.
van der Meijden PE, Schoenwaelder SM, Feijge MA, Cosemans JM, Munnix IC, Wetzker R, Heller R, Jackson SP, Heemskerk JW. van der Meijden PE, et al. FEBS J. 2008 Jan;275(2):371-85. doi: 10.1111/j.1742-4658.2007.06207.x. Epub 2007 Dec 13. FEBS J. 2008. PMID: 18081863 Free article.
Dual role of collagen in factor XII-dependent thrombus formation.
van der Meijden PE, Munnix IC, Auger JM, Govers-Riemslag JW, Cosemans JM, Kuijpers MJ, Spronk HM, Watson SP, Renné T, Heemskerk JW. van der Meijden PE, et al. Blood. 2009 Jul 23;114(4):881-90. doi: 10.1182/blood-2008-07-171066. Epub 2009 Apr 16. Blood. 2009. PMID: 19372258 Free article.
Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation.
Gilio K, Munnix IC, Mangin P, Cosemans JM, Feijge MA, van der Meijden PE, Olieslagers S, Chrzanowska-Wodnicka MB, Lillian R, Schoenwaelder S, Koyasu S, Sage SO, Jackson SP, Heemskerk JW. Gilio K, et al. J Biol Chem. 2009 Dec 4;284(49):33750-62. doi: 10.1074/jbc.M109.048439. Epub 2009 Oct 8. J Biol Chem. 2009. PMID: 19815551 Free PMC article.
77 results