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A high tumour-stroma ratio (TSR) in colon tumours and its metastatic lymph nodes predicts poor cancer-free survival and chemo resistance.
Strous MTA, Faes TKE, Gubbels ALHM, van der Linden RLA, Mesker WE, Bosscha K, Bronkhorst CM, Janssen-Heijnen MLG, Vogelaar FJ, de Bruïne AP. Strous MTA, et al. Among authors: van der linden rla. Clin Transl Oncol. 2022 Jun;24(6):1047-1058. doi: 10.1007/s12094-021-02746-y. Epub 2022 Jan 22. Clin Transl Oncol. 2022. PMID: 35064453
Prognostic implications of occult nodal tumour cells in stage I and II colon cancer: The correlation between micrometastasis and disease recurrence.
Sloothaak DAM, van der Linden RLA, van de Velde CJH, Bemelman WA, Lips DJ, van der Linden JC, Doornewaard H, Tanis PJ, Bosscha K, van der Zaag ES, Buskens CJ. Sloothaak DAM, et al. Among authors: van der linden rla. Eur J Surg Oncol. 2017 Aug;43(8):1456-1462. doi: 10.1016/j.ejso.2017.04.012. Epub 2017 May 5. Eur J Surg Oncol. 2017. PMID: 28576463
Colorectal metastasis to the gallbladder mimicking a primary gallbladder malignancy: histopathological and molecular characteristics.
de Bitter TJJ, van der Linden RLA, van Vliet S, Weren F, Sie D, Ylstra B, van der Linden HC, Knijn N, Ligtenberg MJL, van der Post RS, Simmer F, Nagtegaal ID. de Bitter TJJ, et al. Among authors: van der linden rla. Histopathology. 2019 Sep;75(3):394-404. doi: 10.1111/his.13892. Epub 2019 Jul 18. Histopathology. 2019. PMID: 31044440 Free PMC article.
Multifocal Colorectal Cancer-Do Intraluminal Metastases Occur?
Simmer F, van der Linden RLA, Ligtenberg MJL, Ylstra B, van der Post RS, Nagtegaal ID; Multifocal Colorectal Cancer Study Group. Simmer F, et al. Among authors: van der linden rla. Gastroenterology. 2021 Apr;160(5):1853-1855. doi: 10.1053/j.gastro.2020.12.010. Epub 2020 Dec 13. Gastroenterology. 2021. PMID: 33316233 No abstract available.