van der Kuip H - Search Results

1

Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo.

Hickman JA, Graeser R, de Hoogt R, Vidic S, Brito C, Gutekunst M, van der Kuip H; IMI PREDECT Consortium. Hickman JA, et al. Among authors: van der kuip h. Biotechnol J. 2014 Sep;9(9):1115-28. doi: 10.1002/biot.201300492. Biotechnol J. 2014. PMID: 25174503 Review.

2

Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices.

Davies EJ, Dong M, Gutekunst M, Närhi K, van Zoggel HJ, Blom S, Nagaraj A, Metsalu T, Oswald E, Erkens-Schulze S, Delgado San Martin JA, Turkki R, Wedge SR, af Hällström TM, Schueler J, van Weerden WM, Verschuren EW, Barry ST, van der Kuip H, Hickman JA. Davies EJ, et al. Among authors: van der kuip h. Sci Rep. 2015 Dec 9;5:17187. doi: 10.1038/srep17187. Sci Rep. 2015. PMID: 26647838 Free PMC article.

3

Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project.

de Hoogt R, Estrada MF, Vidic S, Davies EJ, Osswald A, Barbier M, Santo VE, Gjerde K, van Zoggel HJAA, Blom S, Dong M, Närhi K, Boghaert E, Brito C, Chong Y, Sommergruber W, van der Kuip H, van Weerden WM, Verschuren EW, Hickman J, Graeser R. de Hoogt R, et al. Among authors: van der kuip h. Sci Data. 2017 Nov 21;4:170170. doi: 10.1038/sdata.2017.170. Sci Data. 2017. PMID: 29160867 Free PMC article.

4

p53 hypersensitivity is the predominant mechanism of the unique responsiveness of testicular germ cell tumor (TGCT) cells to cisplatin.

Gutekunst M, Oren M, Weilbacher A, Dengler MA, Markwardt C, Thomale J, Aulitzky WE, van der Kuip H. Gutekunst M, et al. Among authors: van der kuip h. PLoS One. 2011 Apr 21;6(4):e19198. doi: 10.1371/journal.pone.0019198. PLoS One. 2011. PMID: 21532991 Free PMC article.

5

Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct-4.

Gutekunst M, Mueller T, Weilbacher A, Dengler MA, Bedke J, Kruck S, Oren M, Aulitzky WE, van der Kuip H. Gutekunst M, et al. Among authors: van der kuip h. Cancer Res. 2013 Mar 1;73(5):1460-9. doi: 10.1158/0008-5472.CAN-12-2876. Epub 2013 Jan 9. Cancer Res. 2013. PMID: 23302226 Free article.

6

RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38.

Weilbacher A, Gutekunst M, Oren M, Aulitzky WE, van der Kuip H. Weilbacher A, et al. Among authors: van der kuip h. Cell Death Dis. 2014 Jul 10;5(7):e1318. doi: 10.1038/cddis.2014.284. Cell Death Dis. 2014. PMID: 25010984 Free PMC article.

7

Imatinib mesylate induces cisplatin hypersensitivity in Bcr-Abl+ cells by differential modulation of p53 transcriptional and proapoptotic activity.

Skorta I, Oren M, Markwardt C, Gutekunst M, Aulitzky WE, van der Kuip H. Skorta I, et al. Among authors: van der kuip h. Cancer Res. 2009 Dec 15;69(24):9337-45. doi: 10.1158/0008-5472.CAN-09-0548. Cancer Res. 2009. PMID: 19934315

8

Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis.

Dengler MA, Staiger AM, Gutekunst M, Hofmann U, Doszczak M, Scheurich P, Schwab M, Aulitzky WE, van der Kuip H. Dengler MA, et al. Among authors: van der kuip h. PLoS One. 2011;6(9):e25139. doi: 10.1371/journal.pone.0025139. Epub 2011 Sep 20. PLoS One. 2011. PMID: 21949869 Free PMC article.

9

Discrepant NOXA (PMAIP1) transcript and NOXA protein levels: a potential Achilles' heel in mantle cell lymphoma.

Dengler MA, Weilbacher A, Gutekunst M, Staiger AM, Vöhringer MC, Horn H, Ott G, Aulitzky WE, van der Kuip H. Dengler MA, et al. Among authors: van der kuip h. Cell Death Dis. 2014 Jan 23;5(1):e1013. doi: 10.1038/cddis.2013.552. Cell Death Dis. 2014. PMID: 24457957 Free PMC article.

10

Imaging of myocardial infarction using ultrasmall superparamagnetic iron oxide nanoparticles: a human study using a multi-parametric cardiovascular magnetic resonance imaging approach.

Yilmaz A, Dengler MA, van der Kuip H, Yildiz H, Rösch S, Klumpp S, Klingel K, Kandolf R, Helluy X, Hiller KH, Jakob PM, Sechtem U. Yilmaz A, et al. Among authors: van der kuip h. Eur Heart J. 2013 Feb;34(6):462-75. doi: 10.1093/eurheartj/ehs366. Epub 2012 Oct 26. Eur Heart J. 2013. PMID: 23103659 Clinical Trial.

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