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Inhibition of TLR4 signalling to dampen joint inflammation in osteoarthritis.
Bartels YL, van Lent PLEM, van der Kraan PM, Blom AB, Bonger KM, van den Bosch MHJ. Bartels YL, et al. Among authors: van der kraan pm. Rheumatology (Oxford). 2024 Mar 1;63(3):608-618. doi: 10.1093/rheumatology/kead493. Rheumatology (Oxford). 2024. PMID: 37788083 Free PMC article. Review.
Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity.
van Meurs J, van Lent P, Stoop R, Holthuysen A, Singer I, Bayne E, Mudgett J, Poole R, Billinghurst C, van der Kraan P, Buma P, van den Berg W. van Meurs J, et al. Arthritis Rheum. 1999 Oct;42(10):2074-84. doi: 10.1002/1529-0131(199910)42:10<2074::AID-ANR7>3.0.CO;2-5. Arthritis Rheum. 1999. PMID: 10524678 Free article.
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation.
Bakker AC, van de Loo FA, van Beuningen HM, Sime P, van Lent PL, van der Kraan PM, Richards CD, van den Berg WB. Bakker AC, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van beuningen hm, van den berg wb. Osteoarthritis Cartilage. 2001 Feb;9(2):128-36. doi: 10.1053/joca.2000.0368. Osteoarthritis Cartilage. 2001. PMID: 11237660 Free article.
Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.
Blom AB, van Lent PL, Libregts S, Holthuysen AE, van der Kraan PM, van Rooijen N, van den Berg WB. Blom AB, et al. Among authors: van der kraan pm, van rooijen n, van lent pl, van den berg wb. Arthritis Rheum. 2007 Jan;56(1):147-57. doi: 10.1002/art.22337. Arthritis Rheum. 2007. PMID: 17195217 Free article.
Cytokine targeting in osteoarthritis.
Blom AB, van der Kraan PM, van den Berg WB. Blom AB, et al. Among authors: van der kraan pm, van den berg wb. Curr Drug Targets. 2007 Feb;8(2):283-92. doi: 10.2174/138945007779940179. Curr Drug Targets. 2007. PMID: 17305506 Review.
Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.
Blaney Davidson EN, Vitters EL, van Lent PL, van de Loo FA, van den Berg WB, van der Kraan PM. Blaney Davidson EN, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van den berg wb. Arthritis Res Ther. 2007;9(5):R102. doi: 10.1186/ar2305. Arthritis Res Ther. 2007. PMID: 17922907 Free PMC article.
254 results