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Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Ke YD, van Hummel A, Au C, Chan G, Lee WS, van der Hoven J, Przybyla M, Deng Y, Sabale M, Morey N, Bertz J, Feiten A, Ippati S, Stevens CH, Yang S, Gladbach A, Haass NK, Kril JJ, Blair IP, Delerue F, Ittner LM. Ke YD, et al. Among authors: van der hoven j. Neuron. 2024 Apr 17;112(8):1249-1264.e8. doi: 10.1016/j.neuron.2024.01.022. Epub 2024 Feb 15. Neuron. 2024. PMID: 38366598
Treatment of epilepsy using a targeted p38γ kinase gene therapy.
Morey N, Przybyla M, van der Hoven J, Ke YD, Delerue F, van Eersel J, Ittner LM. Morey N, et al. Among authors: van der hoven j. Sci Adv. 2022 Dec 2;8(48):eadd2577. doi: 10.1126/sciadv.add2577. Epub 2022 Dec 2. Sci Adv. 2022. PMID: 36459557 Free PMC article.
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
Deng Y, Bi M, Delerue F, Forrest SL, Chan G, van der Hoven J, van Hummel A, Feiten AF, Lee S, Martinez-Valbuena I, Karl T, Kovacs GG, Morahan G, Ke YD, Ittner LM. Deng Y, et al. Among authors: van der hoven j. Acta Neuropathol. 2022 Oct;144(4):637-650. doi: 10.1007/s00401-022-02457-w. Epub 2022 Jul 3. Acta Neuropathol. 2022. PMID: 35780436 Free PMC article.
Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity.
Ippati S, Deng Y, van der Hoven J, Heu C, van Hummel A, Chua SW, Paric E, Chan G, Feiten A, Fath T, Ke YD, Haass NK, Ittner LM. Ippati S, et al. Among authors: van der hoven j. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2011876118. doi: 10.1073/pnas.2011876118. Proc Natl Acad Sci U S A. 2021. PMID: 33737393 Free PMC article.
Onset of hippocampal network aberration and memory deficits in P301S tau mice are associated with an early gene signature.
Przybyla M, van Eersel J, van Hummel A, van der Hoven J, Sabale M, Harasta A, Müller J, Gajwani M, Prikas E, Mueller T, Stevens CH, Power J, Housley GD, Karl T, Kassiou M, Ke YD, Ittner A, Ittner LM. Przybyla M, et al. Among authors: van der hoven j. Brain. 2020 Jun 1;143(6):1889-1904. doi: 10.1093/brain/awaa133. Brain. 2020. PMID: 32375177
20 results