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118 results

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Page 1
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, Schilling M, Jørgensen SE, Thomsen M, Reinert LS, Lappe M, Hoang HD, Gilchrist VH, Hansen AL, Ottosen R, Nielsen CG, Møller C, van der Horst D, Peri S, Balachandran S, Huang J, Jakobsen M, Svenningsen EB, Poulsen TB, Bartsch L, Thielke AL, Luo Y, Alain T, Rehwinkel J, Alcamí A, Hiscott J, Mogensen TH, Paludan SR, Holm CK. Olagnier D, et al. Among authors: van der horst d. Nat Commun. 2020 Oct 2;11(1):4938. doi: 10.1038/s41467-020-18764-3. Nat Commun. 2020. PMID: 33009401 Free PMC article.
Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, Schilling M, Jørgensen SE, Thomsen M, Reinert LS, Lappe M, Hoang HD, Gilchrist VH, Hansen AL, Ottosen R, Nielsen CG, Møller C, van der Horst D, Peri S, Balachandran S, Huang J, Jakobsen M, Svenningsen EB, Poulsen TB, Bartsch L, Thielke AL, Luo Y, Alain T, Rehwinkel J, Alcamí A, Hiscott J, Mogensen TH, Paludan SR, Holm CK. Olagnier D, et al. Among authors: van der horst d. Nat Commun. 2020 Oct 21;11(1):5419. doi: 10.1038/s41467-020-19363-y. Nat Commun. 2020. PMID: 33087717 Free PMC article.
Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans.
Hait AS, Olagnier D, Sancho-Shimizu V, Skipper KA, Helleberg M, Larsen SM, Bodda C, Moldovan LI, Ren F, Brinck Andersen NS, Thomsen MM, Freytag MR, Darmalinggam S, Parkes I, Kadekar DD, Rahbek SH, van der Horst D, Kristensen LS, Eriksson K, Kjems J, Mostowy S, Christiansen M, Mikkelsen JG, Brandt CT, Paludan SR, Mogensen TH. Hait AS, et al. Among authors: van der horst d. Sci Immunol. 2020 Dec 11;5(54):eabc2691. doi: 10.1126/sciimmunol.abc2691. Sci Immunol. 2020. PMID: 33310865 Free PMC article.
Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern.
Carter-Timofte ME, Arulanandam R, Kurmasheva N, Fu K, Laroche G, Taha Z, van der Horst D, Cassin L, van der Sluis RM, Palermo E, Di Carlo D, Jacobs D, Maznyi G, Azad T, Singaravelu R, Ren F, Hansen AL, Idorn M, Holm CK, Jakobsen MR, van Grevenynghe J, Hiscott J, Paludan SR, Bell JC, Seguin J, Sabourin LA, Côté M, Diallo JS, Alain T, Olagnier D. Carter-Timofte ME, et al. Among authors: van der sluis rm, van grevenynghe j, van der horst d. ACS Infect Dis. 2021 Nov 12;7(11):3034-3051. doi: 10.1021/acsinfecdis.1c00278. Epub 2021 Oct 18. ACS Infect Dis. 2021. PMID: 34658235
Regulation of innate immunity by Nrf2.
van der Horst D, Carter-Timofte ME, van Grevenynghe J, Laguette N, Dinkova-Kostova AT, Olagnier D. van der Horst D, et al. Curr Opin Immunol. 2022 Oct;78:102247. doi: 10.1016/j.coi.2022.102247. Epub 2022 Sep 26. Curr Opin Immunol. 2022. PMID: 36174411 Free article. Review.
The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation.
Farahani E, Reinert LS, Narita R, Serrero MC, Skouboe MK, van der Horst D, Assil S, Zhang B, Iversen MB, Gutierrez E, Hazrati H, Johannsen M, Olagnier D, Kunze R, Denham M, Mogensen TH, Lappe M, Paludan SR. Farahani E, et al. Among authors: van der horst d. Cell Rep. 2024 Feb 27;43(2):113792. doi: 10.1016/j.celrep.2024.113792. Epub 2024 Feb 15. Cell Rep. 2024. PMID: 38363679 Free PMC article.
SAM68 directs STING signaling to apoptosis in macrophages.
van der Horst D, Kurmasheva N, Marqvorsen MHS, Assil S, Rahimic AHF, Kollmann CF, Silva da Costa L, Wu Q, Zhao J, Cesari E, Iversen MB, Ren F, Jensen TI, Narita R, Schack VR, Zhang BC, Bak RO, Sette C, Fenton RA, Mikkelsen JG, Paludan SR, Olagnier D. van der Horst D, et al. Commun Biol. 2024 Mar 7;7(1):283. doi: 10.1038/s42003-024-05969-1. Commun Biol. 2024. PMID: 38454028 Free PMC article.
Variation Between Hospitals in Outcomes and Costs of IBD Care: Results From the IBD Value Study.
van Linschoten RCA, van der Woude CJ, Visser E, van Leeuwen N, Bodelier AGL, Fitzpatrick C, de Jonge V, Vermeulen H, Verweij KE, van der Wiel S, Nieboer D, Birnie E, van der Horst D, Hazelzet JA, van Noord D, West RL. van Linschoten RCA, et al. Among authors: van der horst d. Inflamm Bowel Dis. 2024 Apr 26:izae095. doi: 10.1093/ibd/izae095. Online ahead of print. Inflamm Bowel Dis. 2024. PMID: 38666643
Optimising surgical anastomosis in ileocolic resection for Crohn's disease with respect to recurrence and functionality: two international parallel randomized controlled trials comparing handsewn (END-to-end or Kono-S) to stapled anastomosis (HAND2END and the End2End STUDIES).
Haanappel AEG, Bellato V, Buskens CJ, Armuzzi A, van der Bilt JDW, de Boer NKH, Danese S, van der Does de Willebois EML, Duijvestein M, van der Horst D, Pellino G, Richir MC, Selvaggi F, Spinelli A, Vignali A, Rosati R, Bemelman WA. Haanappel AEG, et al. Among authors: van der horst d. BMC Surg. 2024 Feb 26;24(1):71. doi: 10.1186/s12893-024-02340-3. BMC Surg. 2024. PMID: 38408943 Free PMC article. Clinical Trial.
118 results