van der Heyden MAG - Search Results

1

Towards the Development of AgoKirs: New Pharmacological Activators to Study K_ir2.x Channel and Target Cardiac Disease.

van der Schoor L, van Hattum EJ, de Wilde SM, Harlianto NI, van Weert AJ, Bloothooft M, van der Heyden MAG. van der Schoor L, et al. Among authors: van weert aj, van der heyden mag, van hattum ej. Int J Mol Sci. 2020 Aug 11;21(16):5746. doi: 10.3390/ijms21165746. Int J Mol Sci. 2020. PMID: 32796537 Free PMC article. Review.

2

Inhibition of cardiomyocyte automaticity by electrotonic application of inward rectifier current from Kir2.1 expressing cells.

de Boer TP, van Veen TA, Houtman MJ, Jansen JA, van Amersfoorth SC, Doevendans PA, Vos MA, van der Heyden MA. de Boer TP, et al. Med Biol Eng Comput. 2006 Jul;44(7):537-42. doi: 10.1007/s11517-006-0059-8. Epub 2006 Apr 20. Med Biol Eng Comput. 2006. PMID: 16937189

3

Lysosome mediated Kir2.1 breakdown directly influences inward rectifier current density.

Jansen JA, de Boer TP, Wolswinkel R, van Veen TA, Vos MA, van Rijen HV, van der Heyden MA. Jansen JA, et al. Biochem Biophys Res Commun. 2008 Mar 14;367(3):687-92. doi: 10.1016/j.bbrc.2007.12.168. Epub 2008 Jan 7. Biochem Biophys Res Commun. 2008. PMID: 18182162

4

Human cardiomyocyte progenitor cell-derived cardiomyocytes display a maturated electrical phenotype.

de Boer TP, van Veen TA, Jonsson MK, Kok BG, Metz CH, Sluijter JP, Doevendans PA, de Bakker JM, Goumans MJ, van der Heyden MA. de Boer TP, et al. J Mol Cell Cardiol. 2010 Jan;48(1):254-60. doi: 10.1016/j.yjmcc.2009.05.004. Epub 2009 May 19. J Mol Cell Cardiol. 2010. PMID: 19460390

5

The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel.

de Boer TP, Nalos L, Stary A, Kok B, Houtman MJ, Antoons G, van Veen TA, Beekman JD, de Groot BL, Opthof T, Rook MB, Vos MA, van der Heyden MA. de Boer TP, et al. Br J Pharmacol. 2010 Apr;159(7):1532-41. doi: 10.1111/j.1476-5381.2010.00658.x. Epub 2010 Feb 24. Br J Pharmacol. 2010. PMID: 20180941 Free PMC article.

6

The mammalian K(IR)2.x inward rectifier ion channel family: expression pattern and pathophysiology.

de Boer TP, Houtman MJ, Compier M, van der Heyden MA. de Boer TP, et al. Acta Physiol (Oxf). 2010 Jul 1;199(3):243-56. doi: 10.1111/j.1748-1716.2010.02108.x. Epub 2010 Mar 13. Acta Physiol (Oxf). 2010. PMID: 20331539 Review.

7

Inhibition of lysosomal degradation rescues pentamidine-mediated decreases of K(IR)2.1 ion channel expression but not that of K(v)11.1.

Nalos L, de Boer TP, Houtman MJ, Rook MB, Vos MA, van der Heyden MA. Nalos L, et al. Eur J Pharmacol. 2011 Feb 10;652(1-3):96-103. doi: 10.1016/j.ejphar.2010.10.093. Epub 2010 Nov 27. Eur J Pharmacol. 2011. PMID: 21114988

8

Deciphering hERG channels: molecular basis of the rapid component of the delayed rectifier potassium current.

Jonsson MK, van der Heyden MA, van Veen TA. Jonsson MK, et al. J Mol Cell Cardiol. 2012 Sep;53(3):369-74. doi: 10.1016/j.yjmcc.2012.06.011. Epub 2012 Jun 26. J Mol Cell Cardiol. 2012. PMID: 22742967 Review.

9

Inhibition of cardiac inward rectifier currents by cationic amphiphilic drugs.

van der Heyden MA, Stary-Weinzinger A, Sanchez-Chapula JA. van der Heyden MA, et al. Curr Mol Med. 2013 Sep;13(8):1284-98. doi: 10.2174/15665240113139990043. Curr Mol Med. 2013. PMID: 23448372 Review.

10

Cardiac ion channel trafficking defects and drugs.

de Git KC, de Boer TP, Vos MA, van der Heyden MA. de Git KC, et al. Pharmacol Ther. 2013 Jul;139(1):24-31. doi: 10.1016/j.pharmthera.2013.03.008. Epub 2013 Apr 2. Pharmacol Ther. 2013. PMID: 23558293 Review.

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