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Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension.
Van der Feen DE, Kurakula K, Tremblay E, Boucherat O, Bossers GPL, Szulcek R, Bourgeois A, Lampron MC, Habbout K, Martineau S, Paulin R, Kulikowski E, Jahagirdar R, Schalij I, Bogaard HJ, Bartelds B, Provencher S, Berger RMF, Bonnet S, Goumans MJ. Van der Feen DE, et al. Am J Respir Crit Care Med. 2019 Oct 1;200(7):910-920. doi: 10.1164/rccm.201812-2275OC. Am J Respir Crit Care Med. 2019. PMID: 31042405
Cellular senescence impairs the reversibility of pulmonary arterial hypertension.
van der Feen DE, Bossers GPL, Hagdorn QAJ, Moonen JR, Kurakula K, Szulcek R, Chappell J, Vallania F, Donato M, Kok K, Kohli JS, Petersen AH, van Leusden T, Demaria M, Goumans MTH, De Boer RA, Khatri P, Rabinovitch M, Berger RMF, Bartelds B. van der Feen DE, et al. Sci Transl Med. 2020 Jul 29;12(554):eaaw4974. doi: 10.1126/scitranslmed.aaw4974. Sci Transl Med. 2020. PMID: 32727916 Free PMC article.
A novel method optimizing the normalization of cardiac parameters in small animal models: the importance of dimensional indexing.
Hagdorn QAJ, Bossers GPL, Koop AC, Piek A, Eijgenraam TR, van der Feen DE, Silljé HHW, de Boer RA, Berger RMF. Hagdorn QAJ, et al. Among authors: van der feen de. Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1552-H1557. doi: 10.1152/ajpheart.00182.2019. Epub 2019 Apr 12. Am J Physiol Heart Circ Physiol. 2019. PMID: 30978120 Free article.
Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling.
Kurakula K, Hagdorn QAJ, van der Feen DE, Vonk Noordegraaf A, Ten Dijke P, de Boer RA, Bogaard HJ, Goumans MJ, Berger RMF. Kurakula K, et al. Among authors: van der feen de. Angiogenesis. 2022 Feb;25(1):99-112. doi: 10.1007/s10456-021-09812-7. Epub 2021 Aug 11. Angiogenesis. 2022. PMID: 34379232 Free PMC article.
17 results