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Baculovirus-Free SARS-CoV-2 Virus-like Particle Production in Insect Cells for Rapid Neutralization Assessment.
Jaron M, Lehky M, Zarà M, Zaydowicz CN, Lak A, Ballmann R, Heine PA, Wenzel EV, Schneider KT, Bertoglio F, Kempter S, Köster RW, Barbieri SS, van den Heuvel J, Hust M, Dübel S, Schubert M. Jaron M, et al. Among authors: van den heuvel j. Viruses. 2022 Sep 20;14(10):2087. doi: 10.3390/v14102087. Viruses. 2022. PMID: 36298643 Free PMC article.
Baculovirus-free insect cell expression system for high yield antibody and antigen production.
Korn J, Schäckermann D, Kirmann T, Bertoglio F, Steinke S, Heisig J, Ruschig M, Rojas G, Langreder N, Wenzel EV, Roth KDR, Becker M, Meier D, van den Heuvel J, Hust M, Dübel S, Schubert M. Korn J, et al. Among authors: van den heuvel j. Sci Rep. 2020 Dec 7;10(1):21393. doi: 10.1038/s41598-020-78425-9. Sci Rep. 2020. PMID: 33288836 Free PMC article.
A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations.
Bertoglio F, Fühner V, Ruschig M, Heine PA, Abassi L, Klünemann T, Rand U, Meier D, Langreder N, Steinke S, Ballmann R, Schneider KT, Roth KDR, Kuhn P, Riese P, Schäckermann D, Korn J, Koch A, Chaudhry MZ, Eschke K, Kim Y, Zock-Emmenthal S, Becker M, Scholz M, Moreira GMSG, Wenzel EV, Russo G, Garritsen HSP, Casu S, Gerstner A, Roth G, Adler J, Trimpert J, Hermann A, Schirrmann T, Dübel S, Frenzel A, Van den Heuvel J, Čičin-Šain L, Schubert M, Hust M. Bertoglio F, et al. Among authors: van den heuvel j. Cell Rep. 2021 Jul 27;36(4):109433. doi: 10.1016/j.celrep.2021.109433. Epub 2021 Jul 7. Cell Rep. 2021. PMID: 34273271 Free PMC article.
A So-Far Overlooked Secondary Conformation State in the Binding Mode of SARS-CoV-2 Spike Protein to Human ACE2 and Its Conversion Rate Are Crucial for Estimating Infectivity Efficacy of the Underlying Virus Variant.
Sevenich M, van den Heuvel J, Gering I, Mohrlüder J, Willbold D. Sevenich M, et al. Among authors: van den heuvel j. J Virol. 2022 Jul 13;96(13):e0068522. doi: 10.1128/jvi.00685-22. Epub 2022 Jun 8. J Virol. 2022. PMID: 35674432 Free PMC article.
319 results