van den Heuvel FAJ - Search Results

1

The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.

Erdem A, Marin S, Pereira-Martins DA, Cortés R, Cunningham A, Pruis MG, de Boer B, van den Heuvel FAJ, Geugien M, Wierenga ATJ, Brouwers-Vos AZ, Rego EM, Huls G, Cascante M, Schuringa JJ. Erdem A, et al. Among authors: van den heuvel faj. Nat Commun. 2022 Mar 1;13(1):1105. doi: 10.1038/s41467-022-28737-3. Nat Commun. 2022. PMID: 35232995 Free PMC article.

2

Dietary methionine starvation impairs acute myeloid leukemia progression.

Cunningham A, Erdem A, Alshamleh I, Geugien M, Pruis M, Pereira-Martins DA, van den Heuvel FAJ, Wierenga ATJ, Ten Berge H, Dennebos R, van den Boom V, Hogeling SM, Weinhäuser I, Knops R, de Blaauw P, Heiner-Fokkema MR, Woolthuis C, Günther UL, Rego EM, Martens JHA, Jansen JH, Schwalbe H, Huls G, Schuringa JJ. Cunningham A, et al. Among authors: van den heuvel faj. Blood. 2022 Nov 10;140(19):2037-2052. doi: 10.1182/blood.2022017575. Blood. 2022. PMID: 35984907 Free article.

3

Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis.

Folkerts H, Wierenga AT, van den Heuvel FA, Woldhuis RR, Kluit DS, Jaques J, Schuringa JJ, Vellenga E. Folkerts H, et al. Cell Death Dis. 2019 May 29;10(6):421. doi: 10.1038/s41419-019-1648-4. Cell Death Dis. 2019. PMID: 31142733 Free PMC article.

4

CD34⁺ acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax.

Mattes K, Gerritsen M, Folkerts H, Geugien M, van den Heuvel FA, Svendsen AF, Yi G, Martens JHA, Vellenga E. Mattes K, et al. Haematologica. 2020 Aug;105(8):e399-e403. doi: 10.3324/haematol.2019.229997. Epub 2019 Nov 14. Haematologica. 2020. PMID: 31727766 Free PMC article. No abstract available.

5

Sinusoidal endothelial cells are damaged and display enhanced autophagy in myelodysplastic syndromes.

Houwerzijl EJ, van den Heuvel FA, Blom NR, van der Want JJ, Mulder AB, Vellenga E. Houwerzijl EJ, et al. Br J Haematol. 2013 May;161(3):443-6. doi: 10.1111/bjh.12227. Epub 2013 Jan 30. Br J Haematol. 2013. PMID: 23360384 Free article. No abstract available.

6

Erythroid progenitors from patients with low-risk myelodysplastic syndromes are dependent on the surrounding micro environment for their survival.

Folkerts H, Hazenberg CL, Houwerzijl EJ, van den Heuvel FA, Mulder AB, van der Want JJ, Vellenga E. Folkerts H, et al. Exp Hematol. 2015 Mar;43(3):215-222.e2. doi: 10.1016/j.exphem.2014.11.005. Epub 2014 Nov 20. Exp Hematol. 2015. PMID: 25462021 Free article.

7

Tissue distribution of the death ligand TRAIL and its receptors.

Spierings DC, de Vries EG, Vellenga E, van den Heuvel FA, Koornstra JJ, Wesseling J, Hollema H, de Jong S. Spierings DC, et al. J Histochem Cytochem. 2004 Jun;52(6):821-31. doi: 10.1369/jhc.3A6112.2004. J Histochem Cytochem. 2004. PMID: 15150291

8

TAF(II)170 interacts with the concave surface of TATA-binding protein to inhibit its DNA binding activity.

Pereira LA, van der Knaap JA, van den Boom V, van den Heuvel FA, Timmers HT. Pereira LA, et al. Mol Cell Biol. 2001 Nov;21(21):7523-34. doi: 10.1128/MCB.21.21.7523-7534.2001. Mol Cell Biol. 2001. PMID: 11585931 Free PMC article.

9

Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis.

Hougardy BM, Maduro JH, van der Zee AG, de Groot DJ, van den Heuvel FA, de Vries EG, de Jong S. Hougardy BM, et al. Int J Cancer. 2006 Apr 15;118(8):1892-900. doi: 10.1002/ijc.21580. Int J Cancer. 2006. PMID: 16287099 Free article.

10

Sensitivity to Fas-mediated apoptosis in high-risk HPV-positive human cervical cancer cells: relationship with Fas, caspase-8, and Bid.

Hougardy BM, van der Zee AG, van den Heuvel FA, Timmer T, de Vries EG, de Jong S. Hougardy BM, et al. Gynecol Oncol. 2005 May;97(2):353-64. doi: 10.1016/j.ygyno.2005.01.036. Gynecol Oncol. 2005. PMID: 15863130

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