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A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age-dependent differences in absorption.
Streekstra EJ, Kiss M, van den Heuvel J, Nicolaï J, van den Broek P, Botden SMBI, Stommel MWJ, van Rijssel L, Ungell AL, van de Steeg E, Russel FGM, de Wildt SN. Streekstra EJ, et al. Among authors: van den broek p. Clin Transl Sci. 2022 Oct;15(10):2392-2402. doi: 10.1111/cts.13368. Epub 2022 Aug 12. Clin Transl Sci. 2022. PMID: 35962572 Free PMC article.
Completing the Enalaprilat Excretion Pathway-Renal Handling by the Proximal Tubule.
Smeets NJL, Litjens CHC, van den Heuvel JJMW, van Hove H, van den Broek P, Russel FGM, Koenderink JB, de Wildt SN. Smeets NJL, et al. Among authors: van den broek p, van hove h, van den heuvel jjmw. Pharmaceutics. 2020 Sep 30;12(10):935. doi: 10.3390/pharmaceutics12100935. Pharmaceutics. 2020. PMID: 33007874 Free PMC article.
Assessment of Placental Disposition of Infliximab and Etanercept in Women With Autoimmune Diseases and in the Ex Vivo Perfused Placenta.
Eliesen GAM, van Drongelen J, van Hove H, Kooijman NI, van den Broek P, de Vries A, Roeleveld N, Russel FGM, Greupink R. Eliesen GAM, et al. Among authors: van den broek p, van drongelen j, van hove h. Clin Pharmacol Ther. 2020 Jul;108(1):99-106. doi: 10.1002/cpt.1827. Epub 2020 Apr 8. Clin Pharmacol Ther. 2020. PMID: 32153014 Free PMC article.
Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.
van den Brand JA, Mutsaers HA, van Zuilen AD, Blankestijn PJ, van den Broek PH, Russel FG, Masereeuw R, Wetzels JF. van den Brand JA, et al. PLoS One. 2016 Dec 29;11(12):e0168117. doi: 10.1371/journal.pone.0168117. eCollection 2016. PLoS One. 2016. PMID: 28033375 Free PMC article. Clinical Trial.
Bioengineered kidney tubules efficiently excrete uremic toxins.
Jansen J, Fedecostante M, Wilmer MJ, Peters JG, Kreuser UM, van den Broek PH, Mensink RA, Boltje TJ, Stamatialis D, Wetzels JF, van den Heuvel LP, Hoenderop JG, Masereeuw R. Jansen J, et al. Among authors: van den heuvel lp, van den broek ph. Sci Rep. 2016 May 31;6:26715. doi: 10.1038/srep26715. Sci Rep. 2016. PMID: 27242131 Free PMC article.
555 results