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Lead optimization of aryl hydrocarbon receptor ligands for treatment of inflammatory skin disorders.
Rikken G, Smith KJ, van den Brink NJM, Smits JPH, Gowda K, Alnemri A, Kuzu GE, Murray IA, Lin JM, Smits JGA, van Vlijmen-Willems IM, Amin SG, Perdew GH, van den Bogaard EH. Rikken G, et al. Among authors: van den brink njm. Biochem Pharmacol. 2023 Feb;208:115400. doi: 10.1016/j.bcp.2022.115400. Epub 2022 Dec 24. Biochem Pharmacol. 2023. PMID: 36574884 Free article.
Targeting the Cutaneous Microbiota in Atopic Dermatitis by Coal Tar via AHR-Dependent Induction of Antimicrobial Peptides.
Smits JPH, Ederveen THA, Rikken G, van den Brink NJM, van Vlijmen-Willems IMJJ, Boekhorst J, Kamsteeg M, Schalkwijk J, van Hijum SAFT, Zeeuwen PLJM, van den Bogaard EH. Smits JPH, et al. Among authors: van den brink njm. J Invest Dermatol. 2020 Feb;140(2):415-424.e10. doi: 10.1016/j.jid.2019.06.142. Epub 2019 Jul 22. J Invest Dermatol. 2020. PMID: 31344386 Free article. Clinical Trial.
Investigations into the FLG Null Phenotype: Showcasing the Methodology for CRISPR/Cas9 Editing of Human Keratinocytes.
Smits JPH, van den Brink NJM, Meesters LD, Hamdaoui H, Niehues H, Jansen PAM, van Vlijmen-Willems IMJJ, Rodijk-Olthuis D, Evrard C, Poumay Y, van Geel M, Hendriks WJAJ, Schalkwijk J, Zeeuwen PLJM, van den Bogaard EH. Smits JPH, et al. Among authors: van den brink njm. J Invest Dermatol. 2023 Aug;143(8):1520-1528.e5. doi: 10.1016/j.jid.2023.02.021. Epub 2023 Mar 7. J Invest Dermatol. 2023. PMID: 36893939 Free article.
The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A.
Smits JPH, Qu J, Pardow F, van den Brink NJM, Rodijk-Olthuis D, van Vlijmen-Willems IMJJ, van Heeringen SJ, Zeeuwen PLJM, Schalkwijk J, Zhou H, van den Bogaard EH. Smits JPH, et al. Among authors: van den brink njm. bioRxiv [Preprint]. 2023 Jun 8:2023.06.07.544032. doi: 10.1101/2023.06.07.544032. bioRxiv. 2023. PMID: 37333234 Free PMC article. Updated. Preprint.
The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A.
Smits JPH, Qu J, Pardow F, van den Brink NJM, Rodijk-Olthuis D, van Vlijmen-Willems IMJJ, van Heeringen SJ, Zeeuwen PLJM, Schalkwijk J, Zhou H, van den Bogaard EH. Smits JPH, et al. Among authors: van den brink njm. J Invest Dermatol. 2024 Feb 22:S0022-202X(24)00114-3. doi: 10.1016/j.jid.2024.01.030. Online ahead of print. J Invest Dermatol. 2024. PMID: 38401701
Challenges in Noninvasive Skin Biomarker Measurements in Daily Practice: A Longitudinal Study on Skin Surface Protein Detection by the Transdermal Analysis Patch in Pediatric Psoriasis.
Schaap MJ, Bruins FM, van den Brink NJM, Orro K, Groenewoud HMM, de Jong EMGJ, van den Bogaard EH, Seyger MMB. Schaap MJ, et al. Among authors: van den brink njm. Skin Pharmacol Physiol. 2022;35(6):319-327. doi: 10.1159/000527258. Epub 2022 Oct 6. Skin Pharmacol Physiol. 2022. PMID: 36202075 Free PMC article.