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Microvascular damage in type 1 diabetic patients is reversed in the first year after simultaneous pancreas-kidney transplantation.
Khairoun M, de Koning EJ, van den Berg BM, Lievers E, de Boer HC, Schaapherder AF, Mallat MJ, Rotmans JI, van der Boog PJ, van Zonneveld AJ, de Fijter JW, Rabelink TJ, Reinders ME. Khairoun M, et al. Among authors: van zonneveld aj, van der boog pj, van den berg bm. Am J Transplant. 2013 May;13(5):1272-81. doi: 10.1111/ajt.12182. Epub 2013 Feb 22. Am J Transplant. 2013. PMID: 23433125 Free article.
Glomerular endothelial surface layer acts as a barrier against albumin filtration.
Dane MJ, van den Berg BM, Avramut MC, Faas FG, van der Vlag J, Rops AL, Ravelli RB, Koster BJ, van Zonneveld AJ, Vink H, Rabelink TJ. Dane MJ, et al. Among authors: van der vlag j, van zonneveld aj, van den berg bm. Am J Pathol. 2013 May;182(5):1532-40. doi: 10.1016/j.ajpath.2013.01.049. Epub 2013 Mar 19. Am J Pathol. 2013. PMID: 23518410
Early systemic microvascular damage in pigs with atherogenic diabetes mellitus coincides with renal angiopoietin dysbalance.
Khairoun M, van den Heuvel M, van den Berg BM, Sorop O, de Boer R, van Ditzhuijzen NS, Bajema IM, Baelde HJ, Zandbergen M, Duncker DJ, Rabelink TJ, Reinders ME, van der Giessen WJ, Rotmans JI. Khairoun M, et al. Among authors: van ditzhuijzen ns, van den heuvel m, van den berg bm, van der giessen wj. PLoS One. 2015 Apr 24;10(4):e0121555. doi: 10.1371/journal.pone.0121555. eCollection 2015. PLoS One. 2015. PMID: 25909188 Free PMC article.
Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy.
Boels MG, Avramut MC, Koudijs A, Dane MJ, Lee DH, van der Vlag J, Koster AJ, van Zonneveld AJ, van Faassen E, Gröne HJ, van den Berg BM, Rabelink TJ. Boels MG, et al. Among authors: van der vlag j, van zonneveld aj, van faassen e, van den berg bm. Diabetes. 2016 Aug;65(8):2429-39. doi: 10.2337/db15-1413. Epub 2016 Mar 25. Diabetes. 2016. PMID: 27207530
Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy.
Boels MGS, Koudijs A, Avramut MC, Sol WMPJ, Wang G, van Oeveren-Rietdijk AM, van Zonneveld AJ, de Boer HC, van der Vlag J, van Kooten C, Eulberg D, van den Berg BM, IJpelaar DHT, Rabelink TJ. Boels MGS, et al. Among authors: van oeveren rietdijk am, van der vlag j, van kooten c, van zonneveld aj, van den berg bm. Am J Pathol. 2017 Nov;187(11):2430-2440. doi: 10.1016/j.ajpath.2017.07.020. Epub 2017 Aug 22. Am J Pathol. 2017. PMID: 28837800 Free article.
Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium.
van den Berg BM, Wang G, Boels MGS, Avramut MC, Jansen E, Sol WMPJ, Lebrin F, van Zonneveld AJ, de Koning EJP, Vink H, Gröne HJ, Carmeliet P, van der Vlag J, Rabelink TJ. van den Berg BM, et al. Among authors: van der vlag j, van zonneveld aj. J Am Soc Nephrol. 2019 Oct;30(10):1886-1897. doi: 10.1681/ASN.2019020192. Epub 2019 Jul 15. J Am Soc Nephrol. 2019. PMID: 31308073 Free PMC article.
Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier.
Khalil R, Boels MGS; PALGA Group; van den Berg BM, Bruijn JA, Rabelink TJ, Hogendoorn PCW, Baelde HJ. Khalil R, et al. Among authors: van den berg bm. Mol Genet Genomics. 2022 Mar;297(2):397-405. doi: 10.1007/s00438-022-01854-w. Epub 2022 Feb 1. Mol Genet Genomics. 2022. PMID: 35103870 Free PMC article.
99 results