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T and NK Cells in IL2RG-Deficient Patient 50 Years After Hematopoietic Stem Cell Transplantation.
Melsen JE, van Ostaijen-Ten Dam MM, van den Akker EB, Welters MJP, Heezen KC, Pico-Knijnenburg I, Kolijn PM, Bredius RGM, van Doorn R, Langerak AW, Schilham MW, Lankester AC. Melsen JE, et al. Among authors: van den akker eb, van doorn r, van ostaijen ten dam mm. J Clin Immunol. 2022 Aug;42(6):1205-1222. doi: 10.1007/s10875-022-01279-5. Epub 2022 May 9. J Clin Immunol. 2022. PMID: 35527320 Free PMC article.
Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.
Cordes M, Canté-Barrett K, van den Akker EB, Moretti FA, Kiełbasa SM, Vloemans SA, Garcia-Perez L, Teodosio C, van Dongen JJM, Pike-Overzet K, Reinders MJT, Staal FJT. Cordes M, et al. Among authors: van den akker eb, van dongen jjm. Sci Immunol. 2022 Nov 18;7(77):eade0182. doi: 10.1126/sciimmunol.ade0182. Epub 2022 Nov 11. Sci Immunol. 2022. PMID: 36367948
Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens.
Fuchs KJ, van de Meent M, Honders MW, Khatri I, Kester MGD, Koster EAS, Koutsoumpli G, de Ru AH, van Bergen CAM, van Veelen PA, 't Hoen PAC, van Balen P, van den Akker EB, Veelken JH, Halkes CJM, Falkenburg JHF, Griffioen M. Fuchs KJ, et al. Among authors: van den akker eb. Blood. 2024 May 2;143(18):1856-1872. doi: 10.1182/blood.2023022343. Blood. 2024. PMID: 38427583 Free PMC article.
Genomics of human longevity.
Slagboom PE, Beekman M, Passtoors WM, Deelen J, Vaarhorst AA, Boer JM, van den Akker EB, van Heemst D, de Craen AJ, Maier AB, Rozing M, Mooijaart SP, Heijmans BT, Westendorp RG. Slagboom PE, et al. Among authors: van den akker eb, van heemst d. Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12;366(1561):35-42. doi: 10.1098/rstb.2010.0284. Philos Trans R Soc Lond B Biol Sci. 2011. PMID: 21115528 Free PMC article. Review.
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.
Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE. Deelen J, et al. Among authors: van den akker eb, van duijn cm, van heemst d, van der ouderaa fj, van der breggen r. Aging Cell. 2011 Aug;10(4):686-98. doi: 10.1111/j.1474-9726.2011.00705.x. Epub 2011 May 6. Aging Cell. 2011. PMID: 21418511 Free PMC article.
A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention.
Sampietro ML, Trompet S, Verschuren JJ, Talens RP, Deelen J, Heijmans BT, de Winter RJ, Tio RA, Doevendans PA, Ganesh SK, Nabel EG, Westra HJ, Franke L, van den Akker EB, Westendorp RG, Zwinderman AH, Kastrati A, Koch W, Slagboom PE, de Knijff P, Jukema JW. Sampietro ML, et al. Among authors: van den akker eb. Hum Mol Genet. 2011 Dec 1;20(23):4748-57. doi: 10.1093/hmg/ddr389. Epub 2011 Aug 30. Hum Mol Genet. 2011. PMID: 21878436 Free PMC article.
Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways.
Deelen J, Uh HW, Monajemi R, van Heemst D, Thijssen PE, Böhringer S, van den Akker EB, de Craen AJ, Rivadeneira F, Uitterlinden AG, Westendorp RG, Goeman JJ, Slagboom PE, Houwing-Duistermaat JJ, Beekman M. Deelen J, et al. Among authors: van den akker eb, van heemst d. Age (Dordr). 2013 Feb;35(1):235-49. doi: 10.1007/s11357-011-9340-3. Epub 2011 Nov 24. Age (Dordr). 2013. PMID: 22113349 Free PMC article.
74 results